Evidence map›Paper›PMID 36186707›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2022

Quality of life improvement in patients with bone metastases undergoing palliative radiotherapy.

Verónica Cañón, Alfonso Gómez-Iturriaga, Francisco Casquero, Dirk Rades, Arturo Navarro, Olga Del Hoyo, Virginia Morillo, Patricia Willisch, José Luis López-Guerra, Ana Illescas-Vacas and 3 more

Abstract read
In one paragraph

Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Comparison of twice weekly palliative RT versus continuous hypofractionated palliative RT for painful bone metastases.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
    Article
  6. Percent of remaining life on palliative radiation treatment: solely a function of fractionation?Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Verónica CañónDepartment of Radiation Oncology, Hospital Universitario Marqués de Valdecilla Santander, Spain.
Alfonso Gómez-IturriagaDepartment of Radiation Oncology, Hospital Universitario Cruces/Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Francisco CasqueroDepartment of Radiation Oncology, Hospital Universitario Cruces/Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Dirk RadesDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Arturo NavarroDepartment of Radiation Oncology, Instituto Catalán de Oncología, Barcelona, Spain.
Olga Del HoyoDepartment of Radiation Oncology, Hospital Universitario Cruces/Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Virginia MorilloDepartment of Radiation Oncology, Hospital de Castellón, Castellón, Spain.
Patricia WillischDepartment of Radiation Oncology, Hospital Meixoeiro, Vigo, Spain.
José Luis López-GuerraDepartment of Radiation Oncology, Hospital Virgen del Rocío, Sevilla, Spain.
Ana Illescas-VacasDepartment of Radiation Oncology, Hospital Virgen Macarena, Sevilla, Spain.
Raquel CiervideDepartment of Radiation Oncology, Hospital San Chinarro, Madrid, Spain.
Lorea Martinez-IndartBioinformatics and Statistics Department, Hospital Universitario Cruces/Biocruces Heatlh Research, Barakaldo, Spain.
Jon CacicedoDepartment of Radiation Oncology, Hospital Universitario Cruces/Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of the study was to analyze the impact of palliative radiotherapy on quality of life (QoL) in patients with symptomatic bone metastases. Materials and methods: We present the results from a prospective multicentric study including 128 patients who provided pre- and post-radiotherapy (one month after treatment) brief pain inventory (BPI) assessments. Worst pain was recorded using the BPI (range: 0-10). Pain response was described according to the International Bone Metastases Consensus on palliative radiation. Regarding QoL, for each pre- and post-radiation BPI-questionnaire, scores from the interference domains were summed and averaged to obtain an overall interference score. Results: There was a significant correlation between radiation treatment response and improvement in all functional interference domains except sleeping. Patients > 75 years old presented a significantly higher improvement in general activity, mood and relationships with others compared to patients ≤ 75 years old. Patients presenting a baseline pain score ≥ 8 showed a higher improvement in the general activity item (p = 0.049). There was no statistically significant association between pretreatment ECOG, chemotherapy, primary tumor location and radiation schedule with any of the functional interference items. Conclusions: Patients who report pain relief after palliative radiotherapy also present a better quality of life including physical and psychosocial aspects.

Indexed as

bone metastasespainpalliative radiotherapyquality of life

Identifiers

PMID36186707
PMCPMC9518769

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.