Evidence map›Paper›PMID 36186559›Full record

ArticleJACS Au2022

Biodegradable Block Copolymer-Tannic Acid Glue.

Jongmin Park, Eunsook Park, Siyoung Q Choi, Jingxian Wu, Jihye Park, Hyeonju Lee, Hyungjun Kim, Haeshin Lee, Myungeun Seo

Abstract read
In one paragraph

Article in JACS Au, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jongmin ParkDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Eunsook ParkDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Siyoung Q ChoiDepartment of Chemical and Biomolecular Engineering, KAIST, Daejeon 34141, Korea.ORCID https://orcid.org/0000-0002-6020-3091
Jingxian WuDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Jihye ParkDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0002-4704-5201
Hyeonju LeeDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Hyungjun KimDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0001-8261-9381
Haeshin LeeDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0003-3961-9727
Myungeun SeoDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0002-5218-3502

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioadhesives are becoming an essential and important ingredient in medical science. Despite numerous reports, developing adhesive materials that combine strong adhesion, biocompatibility, and biodegradation remains a challenging task. Here, we present a biocompatible yet biodegradable block copolymer-based waterborne superglue that leads to an application of follicle-free hair transplantation. Our design strategy bridges self-assembled, temperature-sensitive block copolymer nanostructures with tannic acid as a sticky and biodegradable polyphenolic compound. The formulation further uniquely offers step-by-step increases in adhesion strength via heating-cooling cycles. Combining the modular design with the thermal treating process enhances the mechanical properties up to 5 orders of magnitude compared to the homopolymer formulation. This study opens a new direction in bioadhesive formulation strategies utilizing block copolymer nanotechnology for systematic and synergistic control of the material's properties.

Identifiers

PMID36186559
PMCPMC9516699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.