Evidence map›Paper›PMID 36186545›Full record

ReviewCurrent tropical medicine reports2022

Herpesvirus-Associated Encephalitis: an Update.

Elizabeth Matthews, J David Beckham, Amanda L Piquet, Kenneth L Tyler, Lakshmi Chauhan, Daniel M Pastula

Abstract readReview
In one paragraph

Review in Current tropical medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth MatthewsNeuro-Infectious Diseases Group, Department of Neurology and Division of Infectious Diseases, University of Colorado School of Medicine, 12700 E 19th Ave, Mailstop B-182, Aurora, CO 80045 USA.ORCID 0000-0001-9823-9797
J David BeckhamNeuro-Infectious Diseases Group, Department of Neurology and Division of Infectious Diseases, University of Colorado School of Medicine, 12700 E 19th Ave, Mailstop B-182, Aurora, CO 80045 USA.
Amanda L PiquetNeuro-Infectious Diseases Group, Department of Neurology and Division of Infectious Diseases, University of Colorado School of Medicine, 12700 E 19th Ave, Mailstop B-182, Aurora, CO 80045 USA.
Kenneth L TylerNeuro-Infectious Diseases Group, Department of Neurology and Division of Infectious Diseases, University of Colorado School of Medicine, 12700 E 19th Ave, Mailstop B-182, Aurora, CO 80045 USA.
Lakshmi ChauhanNeuro-Infectious Diseases Group, Department of Neurology and Division of Infectious Diseases, University of Colorado School of Medicine, 12700 E 19th Ave, Mailstop B-182, Aurora, CO 80045 USA.
Daniel M PastulaNeuro-Infectious Diseases Group, Department of Neurology and Division of Infectious Diseases, University of Colorado School of Medicine, 12700 E 19th Ave, Mailstop B-182, Aurora, CO 80045 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose of Review: Herpesviruses are a leading cause of encephalitis worldwide. The article reviews the eight human herpesviruses with a focus on recent advances as they pertain to encephalitis. Recent Findings: Notable recent updates include the development of multiplex polymerase chain reaction (PCR)-based panels, which have improved access to PCR tests, especially in rural and resource-limited areas. Despite unchanged treatment recommendations, research is ongoing into novel therapies. There have been recent advances in vaccines, particularly for varicella zoster virus (VZV) which may impact neurologic complications. Finally, the recent discovery of an association between herpes encephalitis and post-infectious autoimmune encephalitis has had a critical impact on the fields of infectious and autoimmune neurology, though there remains much to learn. Summary: Most herpesviruses are neurotropic and must be considered on the differential diagnosis for infectious encephalitis. This article describes recent advances in the diagnosis, treatment, complications, and management of these infections.

Indexed as

Cytomegalovirus encephalitisEpstein-Barr virus encephalitisHerpes encephalitisHHV6 encephalitisPostinfectious autoimmune encephalitisVaricella zoster virus encephalitis

Identifiers

PMID36186545
PMCPMC9510386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.