Evidence map›Paper›PMID 36186488›Full record

Trial reportCardiovascular therapeutics2022

Development and Validation of a Nomogram Model for Predicting the Risk of Readmission in Patients with Heart Failure with Reduced Ejection Fraction within 1 Year.

Yue Hu, Xiaotong Wang, Shengjue Xiao, Chunyan Huan, Huimin Wu, Tao Xu, Minjia Guo, Hong Zhu, Defeng Pan

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Cardiovascular therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yue HuDepartment of General Practice, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0001-8226-666X
Xiaotong WangDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0003-2827-4102
Shengjue XiaoDepartment of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, 87 Dingjiaqiao, Nanjing, Jiangsu 210009, China.ORCID https://orcid.org/0000-0003-2561-3260
Chunyan HuanDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0002-2082-7270
Huimin WuDepartment of General Practice, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0001-8296-0651
Tao XuDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0001-9359-3164
Minjia GuoDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0003-3090-9445
Hong ZhuDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0002-1907-4072
Defeng PanDepartment of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0001-5877-2423

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high incidence of readmission for patients with reduced ejection fraction heart failure (HFrEF) can seriously affect the prognosis. In this study, we aimed to build a simple predictive model to predict the risk of heart failure (HF) readmission in patients with HFrEF within one year of discharge from the hospital. This retrospective study enrolled patients with HFrEF evaluated in the Heart Failure Center of the Affiliated Hospital of Xuzhou Medical University from January 2018 to December 2020. The patients were allocated into the readmission or nonreadmission group, according to whether HF readmission occurred within 1 year of hospital discharge. Subsequently, all patients were randomly divided into training and validation sets in a 7 : 3 ratio. A nomogram was established according to the results of univariate and multivariate logistic regression analysis. Finally, the area under the receiver operating characteristic curve (AUC-ROC), calibration plot, and decision curve analysis (DCA) were used to validate the nomogram. Independent risk factors for HF readmission of patients with HFrEF within 1 year of hospital discharge were as follows: age, body mass index, systolic blood pressure, diabetes mellitus, left ventricular ejection fraction, and angiotensin receptor-neprilysin inhibitors. The AUC-ROC of the training and validation sets were 0.833 (95% confidence interval (CI): 0.793-0.866) and 0.794 (95% CI: 0.727-0.852), respectively, which have an excellent distinguishing ability. The predicted and observed values of the calibration curve also showed good consistency. DCA also confirmed that the nomogram had good clinical value. In conclusion, we constructed an accurate and straightforward nomogram model for predicting the 1-year HF readmission risk in patients with HFrEF. This nomogram can guide early clinical intervention and improve patient prognosis.

Indexed as

Heart FailureHumansNeprilysinNomogramsPatient ReadmissionReceptors, AngiotensinRetrospective StudiesRisk FactorsStroke VolumeVentricular Function, LeftNeprilysinReceptors, Angiotensin

Identifiers

PMID36186488
PMCPMC9507773

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.