Evidence map›Paper›PMID 36186473›Full record

ArticleFrontiers in genetics2022

Nonsynonymous amino acid changes in the α-chain of complement component 5 influence longitudinal susceptibility to

Evans Raballah, Kristen Wilding, Samuel B Anyona, Elly O Munde, Ivy Hurwitz, Clinton O Onyango, Cyrus Ayieko, Christophe G Lambert, Kristan A Schneider, Philip D Seidenberg and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 3 countries.

Evans RaballahUniversity of New Mexico-Kenya Global Health Programs, Kisumu, Kenya.
Kristen WildingTheoretical Biology and Biophysics Group, Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM, United States.
Samuel B AnyonaUniversity of New Mexico-Kenya Global Health Programs, Kisumu, Kenya.
Elly O MundeUniversity of New Mexico-Kenya Global Health Programs, Kisumu, Kenya.
Ivy HurwitzUniversity of New Mexico, Center for Global Health, Department of Internal Medicine, Albuquerque, NM, United States.
Clinton O OnyangoUniversity of New Mexico-Kenya Global Health Programs, Kisumu, Kenya.
Cyrus AyiekoDepartment of Zoology, Maseno University, Maseno, Kenya.
Christophe G LambertUniversity of New Mexico, Center for Global Health, Department of Internal Medicine, Albuquerque, NM, United States.
Kristan A SchneiderDepartment of Applied Computer and Biosciences, University of Applied Sciences Mittweida, Mittweida, Germany.
Philip D SeidenbergUniversity of New Mexico, Department of Emergency Medicine, Albuquerque, NM, United States.
Collins OumaUniversity of New Mexico-Kenya Global Health Programs, Kisumu, Kenya.
Benjamin H McMahonTheoretical Biology and Biophysics Group, Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM, United States.
Qiuying ChengUniversity of New Mexico, Center for Global Health, Department of Internal Medicine, Albuquerque, NM, United States.
Douglas J PerkinsUniversity of New Mexico-Kenya Global Health Programs, Kisumu, Kenya.
Maseno University · KEUniversity of New Mexico · USCenter for Global Health · USLos Alamos National Laboratory · USGreat Lakes University of Kisumu · KEHochschule Mittweida · DEKirinyaga University · KEMasinde Muliro University of Science and Technology · KE

Funding

Partnership for Global Health Research Training Program (Renewal)-Supplement for OBSSR, NCI, NCI-AIDS and NIDCDD43TW010543 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, DAVIDSON HOWES HAMER · 2017 to 2026
$12.1M
Harnessing the Malarial Immunity Omics Landscape in Vaccinated and Unvaccinated Children for Improved Therapeutic StrategiesR01AI130473 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Samuel Bonuke Anyona, Douglas Jay Perkins · 2018 to 2026
$5.6M
TRAINING AND RESEARCH ON SEVERE MALARIAL ANEMIAD43TW005884 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Collins Ouma, Douglas Jay Perkins · 2002 to 2026
$5.2M
Dysregulation of the Human Ubiquitin Proteasome System in Pediatric Severe Malarial AnemiaK43TW011581 · FIC · MASENO UNIVERSITY · PI ANYONA, SAMUEL BONUKE · 2020 to 2023
$280k
FIC NIH HHS D43 TW005884FIC NIH HHS D43 TW010543FIC NIH HHS K43 TW011581NIAID NIH HHS R01 AI130473
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

complement 5malariamissense mutationsP. facliparumsevere malarial anaemia

Identifiers

PMID36186473
PMCPMC9515573
OpenAlexW4297900416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.