Evidence map›Paper›PMID 36185877›Full record

ArticleCureus2022

Neuro-Ophthalmologic Symptoms Associated With the Moderna mRNA COVID-19 Vaccine: A Case Report.

Tejas Raxwal, Zeid Akel, Jotsna Naidu, Koravangala Sundaresh

Abstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tejas RaxwalPreventive Medicine, Access Health Care Physicians, Zephyrhills, USA.
Zeid AkelMedical School, Florida State University, Tallahassee, USA.
Jotsna NaiduInternal Medicine, HCA Florida Trinity Hospital, Trinity, USA.
Koravangala SundareshInfectious Diseases, HCA Florida Trinity Hospital, Trinity, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple neuro-ophthalmological symptoms, such as visual field defects, optic neuritis, and eye movement abnormalities, have been reported with coronavirus disease 2019 (COVID-19) infection. It is unknown whether the COVID-19 vaccine can result in similar neuro-ophthalmological symptoms post-vaccination. Here, we describe a case of optic neuritis after the administration of the mRNA COVID-19 Moderna vaccine. A 47-year-old female presented eight days after receiving the first dose of the Moderna COVID-19 vaccine with impaired vision in the left eye and symptoms consistent with optic neuritis. The patient underwent a workup for infectious etiology, autoimmune diseases, and allergies, which was negative. The patient was treated with a high dose of steroids resulting in the complete resolution of her symptoms. The patient was recommended against the second dose of the mRNA COVID-19 vaccine. Early detection and treatment of optic neuritis are important to prevent the long-term sequelae of neuritis with impaired vision.

Indexed as

coronaviruscovid-19moderna vaccinemrna covid-19 vaccineoptic neuritissars-cov-2

Identifiers

PMID36185877
PMCPMC9516661

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.