Evidence map›Paper›PMID 36185766›Full record

ReviewExperimental and therapeutic medicine2022

Properties of flavonoids in the treatment of bladder cancer (Review).

Yue Lv, Zhonghao Liu, Haixing Jia, Youcheng Xiu, Zan Liu, Leihong Deng

Abstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Unveiling organ-specific metabolism ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Anthocyanins and flavonoids derived fromActa biochimica et biophysica Sinica · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yue LvDepartment of Urology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150000, P.R. China.
Zhonghao LiuDepartment of Urology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150000, P.R. China.
Haixing JiaDepartment of Urology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150000, P.R. China.
Youcheng XiuDepartment of Urology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150000, P.R. China.
Zan LiuDepartment of Urology, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150000, P.R. China.
Leihong DengDepartment of Ultrasound Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given its high recurrence and rapid progress, bladder cancer (BLCA) treatment has become a major problem for clinicians. BLCA is difficult to control even with surgical resection and extensive use of chemotherapeutic drugs. The non-toxicity and ease of accessibility of natural compounds have attracted much attention in recent years. Flavonoids serve an essential role given their antioxidant, antibacterial, anticancer and cardiovascular properties. They are mainly divided into several subclasses; flavones, flavanones, flavonols, flavanols, anthocyanins isoflavones and chalcones. Over the years, the role of flavonoids in BLCA has been extensively studied. The present review provided a comprehensive overview of the classification of flavonoids and substantiate the role of epithelial-mesenchymal transition, cancer stem cells, angiogenesis, epigenetic regulation and programmed cell death in BLCA. The present review emphasized that flavonoids for BLCA treatment are worthy of further study and anti-BLCA drugs have huge prospects for clinical use.

Indexed as

apoptosisbladder cancercell cycleflavonoids

Identifiers

PMID36185766
PMCPMC9522619

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.