Evidence map›Paper›PMID 36185758›Full record

ArticleCurrent addiction reports2021

Parenting and addictions: Current insights from human neuroscience.

Helena Jv Rutherford, Sohye Kim, Sarah W Yip, Marc N Potenza, Linda C Mayes, Lane Strathearn

Abstract read
In one paragraph

Article in Current addiction reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Protective role of parenthood on age-related brain function in mid- to late-life.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Helena Jv RutherfordChild Study Center, Yale University School of Medicine, New Haven, CT 06520, United States.
Sohye KimEunice Kennedy Shriver Center, University of Massachusetts Medical School, Worcester, MA 01655.
Sarah W YipChild Study Center, Yale University School of Medicine, New Haven, CT 06520, United States.
Marc N PotenzaChild Study Center, Yale University School of Medicine, New Haven, CT 06520, United States.
Linda C MayesChild Study Center, Yale University School of Medicine, New Haven, CT 06520, United States.
Lane StrathearnStead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA 52242, United States.

Funding

University of Iowa Hawkeye Intellectual and Developmental Disabilities Research Center (Hawk-IDDRC)P50HD103556 · NICHD · UNIVERSITY OF IOWA · PI Lane Strathearn · 2021 to 2026
$8.5M
Oxytocin and Brain Reward and Stress Responses to Infant Cues in Addicted MothersR01DA026437 · NIDA · UNIVERSITY OF IOWA · PI MAYES, LINDA CAROL, STRATHEARN, LANE · 2010 to 2020
$7.2M
University of Massachusetts Center for Clinical and Translational ScienceKL2TR001455 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2015 to 2024
$5.0M
University of Massachusetts Center for Clinical and Translational ScienceTL1TR001454 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEWIS, BRIAN C · 2015 to 2024
$3.6M
Psychosocial and neurobiological stress and opioid use trajectories following pregnancyR01DA050636 · NIDA · YALE UNIVERSITY · PI RUTHERFORD, HELENA JV, YIP, SARAH · 2020 to 2024
$2.8M
Neural mechanisms of galantamine treatment for cocaine dependenceK01DA039299 · NIDA · YALE UNIVERSITY · PI YIP, SARAH · 2016 to 2020
$905k
NCATS NIH HHS KL2 TR001455NCATS NIH HHS TL1 TR001454NICHD NIH HHS P50 HD103556NIDA NIH HHS K01 DA039299NIDA NIH HHS R01 DA026437NIDA NIH HHS R01 DA050636
6 · The paper itself

Abstract

Purpose: A growing body of human research has documented associations between the maternal brain and maternal substance use and addictions. This neuroscience-informed approach affords the opportunity to unpack potential neurobiological mechanisms that may underscore challenges in maternal caregiving behavior among mothers with addictions and provide new directions for parenting interventions. Findings: Consistent with theoretical models of parenting and addictions, five studies evidence both hypo- and hyper-reactivity to infant affective cues across neuroimaging methods and tasks that incorporate both infant face and cry stimuli. Three structural and resting-state brain studies as a function of maternal substance use are also reported. Conclusions: While human neuroimaging research converges in showing that maternal substance use is associated with differential reactivity to infant affective cues, further multi-level/multi-modal, longitudinal, and dimensional research is critically needed to advance this area of investigation.

Indexed as

addictive behaviorsEEG/ERPfMRIinfant cuesmotherssubstance use

Identifiers

PMID36185758
PMCPMC9523670

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.