ArticleBioactive materials2023
A novel approach for the prevention of ionizing radiation-induced bone loss using a designer multifunctional cerium oxide nanozyme.
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Article in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32citing papers in PubMed
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Who cites it
32 citing papers in PubMed.
- Self-cascade colorimetric sensing of profenofos synergistically driven by phosphatase- and laccase-like activities of Ce-MOF nanozymes.Mikrochimica acta · 2026Article
- Exosomes Derived from BMSCs Treated with CeONPs Ameliorate Radiation-Induced Jaw Bone Injury via miR-21-5p/STAT3 Axis-Mediated Osteogenesis and ROS Scavenging.Pharmaceutics · 2026Article
- Emerging potential of engineered nanozymes in periodontitis treatment: from monotherapy to hierarchical therapy.Journal of nanobiotechnology · 2026Review
- Bone Marrow Mesenchymal Stem Cell Senescence in the Development of Osteoporosis: Mechanisms, Interventions, and Future Directions.Current molecular medicine · 2026Review
- Nanozymes for Bone Regeneration: Mechanistic Insights into Immune and Metabolic Microenvironment Modulation.International journal of nanomedicine · 2026Review
- Black Phosphorus Nanomaterials and the Senescent Osteoimmune Microenvironment: Mechanisms, Opportunities, Challenges, and Future Outlook.International journal of nanomedicine · 2026Review
- Lithium exposure causes ferroptosis to induce unexplained miscarriage through non-canonical MBOAT1 pathway.Nature communications · 2025Article
- Mitochondrial dysfunction in mesenchymal stem cells impairs osteogenesis in radiation-induced bone injury via CaCell death & disease · 2025Article
- Targeting the ROS-ferroptosis-inflammation cycle with a nanozyme-functionalized hydrogel for intervertebral disc repair.Nature communications · 2025Article
- Upregulated GDF-15 in Ankylosing Spondylitis: Pathologic Ossification Promotion through Ligament Fibroblast Osteogenic Differentiation.ACR open rheumatology · 2025Article
- The Buffering Activity of Ceria toward Reactive Oxygen Species: A Density Functional Theory Perspective.The journal of physical chemistry. C, Nanomaterials and interfaces · 2025Article
- Antisenescence therapies for age-related bone loss: Target factors, medicines, biomedical materials.Clinical and translational medicine · 2025Review
- Biomimetic Nanoplatform for Targeted Rheumatoid Arthritis Therapy: Modulating Macrophage Niches Through Self-Sustaining Positive Feedback-Driven Drug Release Mechanisms.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Radiation-Activated Cobalt-Based Zeolite Imidazolate Frameworks for Tumor Multitherapy.Biomaterials research · 2025Article
- Exercise ameliorates osteopenia in mice via intestinal microbial-mediated bile acid metabolism pathway.Theranostics · 2025Article
- Magnesium ion hydrogel enhances resistance to radiation-induced bone injury by modulating the bone immune microenvironment and promoting microvascularization.Regenerative biomaterials · 2025Article
- Cartilage-targeting peptide-modified cerium oxide nanoparticles alleviate oxidative stress and cartilage damage in osteoarthritis.Journal of nanobiotechnology · 2024Article
- Strain Effects on the Adsorption of Water on Cerium Dioxide Surfaces and Nanoparticles: A Modeling Outlook.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024Article
- The biomedical applications of nanozymes in orthopaedics based on regulating reactive oxygen species.Journal of nanobiotechnology · 2024Review
- Biosynthesis of fungus-based oral selenium microcarriers for radioprotection and immuno-homeostasis shaping against radiation-induced heart disease.Bioactive materials · 2024Article
Corrections and comments
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Authors and funding
18 authors.
Fei WeiBiionix Cluster, Department of Internal Medicine, College of Medicine, University of Central Florida, Orlando, FL, USA.
Craig J NealAdvanced Materials Processing and Analysis Centre, Nanoscience Technology Center (NSTC), Materials Science and Engineering, College of Medicine, University of Central Florida, Orlando, FL, USA.
Tamil Selvan SakthivelCMC Materials, 870 North Commons, Dr, Aurora, IL, USA.
Yifei FuAdvanced Materials Processing and Analysis Centre, Nanoscience Technology Center (NSTC), Materials Science and Engineering, College of Medicine, University of Central Florida, Orlando, FL, USA.
Mahmoud OmerBiionix Cluster, Department of Internal Medicine, College of Medicine, University of Central Florida, Orlando, FL, USA.
Amitava AdhikaryDepartment of Chemistry, Oakland University, Rochester, MI, MI, USA.
Samuel WardDepartment of Chemistry, Oakland University, Rochester, MI, MI, USA.
Khoa Minh TaSchool of Applied Sciences, Department of Chemical Sciences, University of Huddersfield, UK.
Samuel MoxonSchool of Applied Sciences, Department of Chemical Sciences, University of Huddersfield, UK.
Marco MolinariSchool of Applied Sciences, Department of Chemical Sciences, University of Huddersfield, UK.
Jackson AsiaticoDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL, USA.
Michael KinzelDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL, USA.
Sergey N YarmolenkoEngineering Research Center for Revolutionizing Biomaterials, North Carolina A & T University, Greensboro, NC, USA.
Vee San CheongDepartment of Automatic Control and Systems Engineering, Insigneo Institute for In Silico Medicine, University of Sheffield, Sheffield, S1 3JD, UK.
Nina OrlovskayaDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL, USA.
Ranajay GhoshDepartment of Mechanical and Aerospace Engineering, University of Central Florida, Orlando, FL, USA.
Sudipta SealBiionix Cluster, Department of Internal Medicine, College of Medicine, University of Central Florida, Orlando, FL, USA.
Melanie CoathupBiionix Cluster, Department of Internal Medicine, College of Medicine, University of Central Florida, Orlando, FL, USA.
Funding
RADIOPROTECTION OF DNA BY THIOLS--OXYGEN AND LET EFFECTSR01CA045424 · NCI · OAKLAND UNIVERSITY · PI SEVILLA, MICHAEL DOUGLAS · 1987 to 2021
$4.2MNCI NIH HHS R01 CA045424
Abstract
The disability, mortality and costs due to ionizing radiation (IR)-induced osteoporotic bone fractures are substantial and no effective therapy exists. Ionizing radiation increases cellular oxidative damage, causing an imbalance in bone turnover that is primarily driven
Indexed as
ALP, Alkaline phosphataseBMSC, Bone marrow derived mesenchymal stem cellsBone resorptionBone strengthCAT, CatalaseCeONPs, Cerium oxide nanoparticlesCerium oxideCOLI, Collagen type ICTSK, Cathepsin KCTX-1, Cross-linked C-telopeptide of type I collagenDFT, Density functional theoryDNA, Deoxyribonucleic acidEPR, Electron paramagnetic resonanceFDA, Food and Drug AdministrationGPX, Glutathione peroxidaseGy, GrayHIF1α, Hypoxia-inducible factor 1 alphaIL-1β, Interleukin 1 betaIL-6, Interleukin 6Ionizing radiationIR, Ionizing radiationMNGC, Multinucleated giant cellNanozymeOCN, OsteocalcinOsteoporosisRANKL, Receptor activator of nuclear factor kappa-Β ligandROS, Reactive oxygen speciesSAED, Selected area electron diffractionSOD, Superoxide dismutaseTRAP, Tartrate-resistant acid phosphataseXPS, X-ray photoelectron spectroscopy
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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.