Evidence map›Paper›PMID 36185611›Full record

ArticleTheranostics2022

Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration.

Shaoxue Zeng, Ting Zhang, Yingying Chen, Joshua Chu-Tan, Kaiyu Jin, So-Ra Lee, Michelle X Yam, Michele C Madigan, Nilisha Fernando, Adrian Cioanca and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shaoxue ZengSave Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Ting ZhangSave Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Yingying ChenSave Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Joshua Chu-TanThe John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Kaiyu JinPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China.
So-Ra LeeSave Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Michelle X YamSave Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Michele C MadiganSave Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Nilisha FernandoThe John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Adrian CioancaThe John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Fanfan ZhouSchool of Pharmacy, The University of Sydney, Sydney, NSW 2006, Australia.
Meidong ZhuSave Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Junjun ZhangDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Riccardo NatoliThe John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Xiaohui FanPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Ling ZhuSave Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.
Mark C GilliesSave Sight Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Retinal DegenerationAnimalsEpendymoglial CellsGlial Fibrillary Acidic ProteinHumansMAP Kinase Signaling SystemMiceTranscription FactorsGlial Fibrillary Acidic ProteinTranscription FactorsMüller cellsPD98059pERK1/2 inhibitionphotoreceptor degeneration

Identifiers

PMID36185611
PMCPMC9516241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.