Evidence map›Paper›PMID 36185442›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Development of biodegradable Zn-Mn-Li and CaP coatings on Zn-Mn-Li alloys and cytocompatibility evaluation for bone graft.

Hui-Fen Qiang, Zhao-Yong Lv, Cai-Yao Hou, Xin Luo, Jun Li, Kun Liu, Chun-Xiu Meng, Wan-Qing Du, Yu-Jue Zhang, Xi-Meng Chen and 1 more

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hui-Fen QiangDepartment of Materials Science and Engineering, Liaocheng University, Liaocheng, China.
Zhao-Yong LvLiaocheng People's Hospital, Dongchangfu Hospital of Liaocheng Hospital, Liaocheng, China.
Cai-Yao HouDepartment of Materials Science and Engineering, Liaocheng University, Liaocheng, China.
Xin LuoLiaocheng People's Hospital, Dongchangfu Hospital of Liaocheng Hospital, Liaocheng, China.
Jun LiLiaocheng People's Hospital, Dongchangfu Hospital of Liaocheng Hospital, Liaocheng, China.
Kun LiuLiaocheng People's Hospital, Dongchangfu Hospital of Liaocheng Hospital, Liaocheng, China.
Chun-Xiu MengLiaocheng People's Hospital, Dongchangfu Hospital of Liaocheng Hospital, Liaocheng, China.
Wan-Qing DuLiaocheng People's Hospital, Dongchangfu Hospital of Liaocheng Hospital, Liaocheng, China.
Yu-Jue ZhangLiaocheng People's Hospital, Dongchangfu Hospital of Liaocheng Hospital, Liaocheng, China.
Xi-Meng ChenLiaocheng People's Hospital, Dongchangfu Hospital of Liaocheng Hospital, Liaocheng, China.
Feng-Zhen LiuDepartment of Materials Science and Engineering, Liaocheng University, Liaocheng, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zn-based alloys are considered as new kind of potential biodegradable implanted biomaterials recently. The difficulty of metal implanted biomaterials and bone tissue integration seriously affects the applications of metal implanted scaffolds in bone tissue-related fields. Herein, we self-designed Zn0.8Mn and Zn0.8Mn0.1Li alloys and CaP coated Zn0.8Mn and Zn0.8Mn0.1Li alloys, then evaluated the degradation property and cytocompatibility. The results demonstrated that the Zn0.8Mn0.1Li alloys had profoundly modified the degradation property and cytocompatibility, but Zn0.8Mn0.1Li alloys had particularly adverse effects on the surface morphology of osteoblasts. The results furtherly showed that the CaP-coated Zn0.8Mn and Zn0.8Mn0.1Li alloys scaffold had better biocompatibility, which would further guarantee the biosafety of this new kind of biodegradable Zn-based alloys implants for future clinical applications.

Indexed as

cytocompatibilitydegradation propertymechanical propertyosteogenesiszn-based alloys

Identifiers

PMID36185442
PMCPMC9515419

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.