Evidence map›Paper›PMID 36185393›Full record

ArticleJournal of computational physics2022

Modeling and simulation of cell nuclear architecture reorganization process.

Qing Cheng, Pourya Delafrouz, Jie Liang, Chun Liu, Jie Shen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of computational physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qing ChengDepartment of Mathematics,Purdue University, West Lafayette, IN 47907, USA.
Pourya DelafrouzDepartment of Bioengineering, University of Illinois at Chicago, SEO, MC-063, Chicago, IL, 60607-7052, USA.
Jie LiangDepartment of Bioengineering, University of Illinois at Chicago, SEO, MC-063, Chicago, IL, 60607-7052, USA.
Chun LiuDepartment of Applied Mathematics, Illinois Institute of Technology, Chicago, IL 60616, USA.
Jie ShenDepartment of Mathematics,Purdue University, West Lafayette, IN 47907, USA.

Funding

Models and Algorithms for Biological Networks and Polymers: Stochastic Probability Landscape and Chromatin EnsemblesR35GM127084 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LIANG, JIE · 2018 to 2025
$3.7M
NIGMS NIH HHS R35 GM127084
6 · The paper itself

Abstract

We develop a special phase field/diffusive interface method to model the nuclear architecture reorganization process. In particular, we use a Lagrange multiplier approach in the phase field model to preserve the specific physical and geometrical constraints for the biological events. We develop several efficient and robust linear and weakly nonlinear schemes for this new model. To validate the model and numerical methods, we present ample numerical simulations which in particular reproduce several processes of nuclear architecture reorganization from the experiment literature.

Indexed as

chromosomeLagrange multiplierNuclear architecture reorganizationPhase field approach

Identifiers

PMID36185393
PMCPMC9524197

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.