ReviewFrontiers in oncology2022
The role of colonic motility in low anterior resection syndrome.
Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Clinical Relevance of the Rectosigmoid Brake in Surgical Disorders and Therapies: A Systematic Review of Colonic Manometry Studies.Neurogastroenterology and motility · 2026Pooled it
- Association between anastomotic leak after rectal resection and bowel dysfunction, a systematic review, meta-analysis and meta-regression.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Pooled it
- A systematic review of preoperative radiological factors associated with the development of low anterior resection syndrome (LARS).Updates in surgery · 2025Pooled it
- Anorectal substructure dosimetry and low anterior resection syndrome after neoadjuvant radiotherapy for rectal cancer: an exploratory analysis.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Understanding the patient perspective in low anterior resection syndrome: which symptoms matter most?Surgery today · 2026Article
- Patient-reported outcomes in low anterior resection syndrome: a comparison of open and robotic surgery.International journal of colorectal disease · 2026Article
- Case Report: Quantitative and qualitative evaluation for electroacupuncture combined with moxibustion in the treatment of recalcitrant low anterior resection syndrome.Frontiers in medicine · 2026Article
- Association between pre-reversal systemic inflammation response index and low anterior resection syndrome in rectal cancer patients: a retrospective cohort study.Frontiers in oncology · 2026Article
- Effects of prune consumption on the incidence of low anterior resection syndrome: a randomized controlled trial.Annals of coloproctology · 2025Article
- The Role of the Greater Omentum Flap in the Prevention of Low Anterior Resection Syndrome (LARS): A Systematic Review of the Literature.Journal of clinical medicine · 2025Review
- Low Anterior Resection Syndrome, Role of SNM?Clinics in colon and rectal surgery · 2025Review
- High output stoma after surgery for rectal cancer - a risk factor for low anterior resection syndrome?BMC gastroenterology · 2025Article
- Application of pelvic floor rehabilitation in patients with colorectal cancer: a scoping review.Techniques in coloproctology · 2024Article
- Risk factors for severe low anterior resection syndrome in patients with rectal cancer undergoing sphincter‑preserving resection: A systematic review and meta‑analysis.Oncology letters · 2024Article
- Low Anterior Resection Syndrome (LARS) after Surgery for Rectal Cancer: An Inevitable Price to Pay for Survival, or a Preventable Complication?Journal of clinical medicine · 2023Article
- Specific Septic Complications after Rectal Cancer Surgery: A Critical Multicentre Study.Cancers · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low anterior resection syndrome (LARS) describes the symptoms and experiences of bowel dysfunction experienced by patients after rectal cancer surgery. LARS is a complex and multifactorial syndrome exacerbated by factors such as low anastomotic height, defunctioning of the colon and neorectum, and radiotherapy. There has recently been growing awareness and understanding regarding the role of colonic motility as a contributing mechanism for LARS. It is well established that rectosigmoid motility serves an important role in coordinating rectal filling and maintaining continence. Resection of the rectosigmoid may therefore contribute to LARS through altered distal colonic and neorectal motility. This review evaluates the role of colonic motility within the broader pathophysiology of LARS and outlines future directions of research needed to enable targeted therapy for specific LARS phenotypes.
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