Evidence map›Paper›PMID 36185182›Full record

ReviewFrontiers in oncology2022

Testicular tumors in the "elderly" population.

Simona Secondino, Giovanni Rosti, Antonino C Tralongo, Franco Nolè, Domiziana Alaimo, Ornella Carminati, Richard Lawrence John Naspro, Paolo Pedrazzoli

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Spermatocytic Tumor: A Review.International journal of molecular sciences · 2023
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Simona SecondinoDepartment of Oncology and Hematology, Medical Oncology Unit, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia, Italy.
Giovanni RostiDepartment of Oncology and Hematology, Medical Oncology Unit, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia, Italy.
Antonino C TralongoMedical Oncology Unit Umberto I Hospital, Rete Assistenza Oncologica (RAO) Department of Oncology, Azienda Sanitaria Provinciale (ASP), Siracusa, Italy.
Franco NolèMedical Oncology Division of Urogenital and Head & Neck Tumours, European Institute of Oncology Istituto di Ricerca e Cura a Carattere Scientifico, Milan, Italy.
Domiziana AlaimoDepartment of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy.
Ornella CarminatiMedical Oncology, Ospedale per gli Infermi, AUSL Romagna, Rimini, Italy.
Richard Lawrence John NasproUrology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Paolo PedrazzoliDepartment of Oncology and Hematology, Medical Oncology Unit, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Germ cell tumors arise in childhood but peak at around 30 years of age. They are the most common cancers in males under the age of 35. Over 95% arise in the testes while a minority originate in extragonadal sites such as the anterior mediastinum, or mainly in childhood the pineal gland or the sacrococcygeal area. These tumors show an extraordinary sensitivity to chemotherapy (and for seminoma, also to radiation) and cure rates are relatively high even in second or subsequent relapses. Very few data are present in the literature regarding patients diagnosed after 50 years and no specific trials have been conducted in this setting. Nearly all patients reported in the literature had testicular cancers, with occasional reports of extragonadal tumors. Despite the fact that > 50 years may be considered an "elderly" population, these patients are treated with the same cisplatin containing combinations as their younger counterparts with consequent higher toxicity. In this review we will present epidemiological and clinical data from this rare population of patients with testicular cancer.

Indexed as

elderly populationgerm cell tumornon-seminomaold cancer patientseminoma

Identifiers

PMID36185182
PMCPMC9523537

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.