Evidence map›Paper›PMID 36185062›Full record

ArticleQuantitative imaging in medicine and surgery2022

Automated volumetric and statistical shape assessment of cam-type morphology of the femoral head-neck region from clinical 3D magnetic resonance images.

Jessica M Bugeja, Ying Xia, Shekhar S Chandra, Nicholas J Murphy, Jillian Eyles, Libby Spiers, Stuart Crozier, David J Hunter, Jurgen Fripp, Craig Engstrom

Abstract read
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Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Jessica M BugejaSchool of Information Technology and Electrical Engineering, The University of Queensland, Brisbane, Australia.
Ying XiaAustralian e-Health Research Centre, Commonwealth Scientific and Industrial Research Organisation, Health and Biosecurity, Herston, Australia.
Shekhar S ChandraSchool of Information Technology and Electrical Engineering, The University of Queensland, Brisbane, Australia.
Nicholas J MurphyKolling Institute of Medical Research, Institute of Bone and Joint Research, University of Sydney, Sydney, Australia.
Jillian EylesKolling Institute of Medical Research, Institute of Bone and Joint Research, University of Sydney, Sydney, Australia.
Libby SpiersCentre for Health, Exercise and Sports Medicine, Department of Physiotherapy, University of Melbourne, Melbourne, Australia.
Stuart CrozierSchool of Information Technology and Electrical Engineering, The University of Queensland, Brisbane, Australia.
David J HunterKolling Institute of Medical Research, Institute of Bone and Joint Research, University of Sydney, Sydney, Australia.
Jurgen FrippAustralian e-Health Research Centre, Commonwealth Scientific and Industrial Research Organisation, Health and Biosecurity, Herston, Australia.
Craig EngstromSchool of Human Movement Studies, The University of Queensland, Brisbane, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Femoroacetabular impingement (FAI) cam morphology is routinely assessed using manual measurements of two-dimensional (2D) alpha angles which are prone to high rater variability and do not provide direct three-dimensional (3D) data on these osseous formations. We present CamMorph, a fully automated 3D pipeline for segmentation, statistical shape assessment and measurement of cam volume, surface area and height from clinical magnetic resonance (MR) images of the hip in FAI patients. Methods: The novel CamMorph pipeline involves two components: (I) accurate proximal femur segmentation generated by combining the 3D U-net to identify both global (region) and local (edge) features in clinical MR images and focused shape modelling to generate a 3D anatomical model for creating patient-specific proximal femur models; (II) patient-specific anatomical information from 3D focused shape modelling to simulate 'healthy' femoral bone models with cam-affected region constraints applied to the anterosuperior femoral head-neck region to quantify cam morphology in FAI patients. The CamMorph pipeline, which generates patient-specific data within 5 min, was used to analyse multi-site clinical MR images of the hip to measure and assess cam morphology in male (n=56) and female (n=41) FAI patients. Results: There was excellent agreement between manual and CamMorph segmentations of the proximal femur as demonstrated by the mean Dice similarity index (DSI; 0.964±0.006), 95% Hausdorff distance (HD; 2.123±0.876 mm) and average surface distance (ASD; 0.539±0.189 mm) values. Compared to female FAI patients, male patients had a significantly larger median cam volume (969.22 Conclusions: The fully automated 3D CamMorph pipeline developed in the present study successfully segmented and measured cam morphology from clinical MR images of the hip in male and female patients with differing FAI severity and pathoanatomical characteristics.

Indexed as

cam-type femoroacetabular impingement syndrome (cam-type FAI syndrome)Hip jointmagnetic resonance imaging (MRI)statistical shape modelling

Identifiers

PMID36185062
PMCPMC9511434

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