ArticleNature communications2022
Schemas provide a scaffold for neocortical integration of new memories over time.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06518421 (The Role of Limbic Subcortical Structures and Cognition in Chronic Neuropathic Pain), which is not on this map. Cited by 42 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Limbic Subcortical Structures and Cognition in Chronic Neuropathic Pain
Who cites it
42 citing papers in PubMed.
- Functional Imaging of Hippocampal Layers Using VASO and BOLD on the Next Generation (NexGen) 7T Scanner.Human brain mapping · 2026Article
- Between the lines: Role of cultural schemas in remembering and forgetting.Memory & cognition · 2026Article
- The hippocampus rapidly integrates sequence representations during novel multistep predictions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Article
- Differential effects of contextual congruency on recognition and retrieval of perceptual details.Memory & cognition · 2026Article
- Natural language processing captures memory content associated with shared neural patterns at encoding and retrieval.Communications psychology · 2026Article
- Ventromedial prefrontal cortex supports prototype representations in healthy older adults.Neurobiology of aging · 2026Article
- Spaces and sequences in the hippocampus: a homological perspective.Journal of computational neuroscience · 2026Article
- The Development of Hippocampal-Cortical Functional Connectivity in Infants and Toddlers.Human brain mapping · 2026Article
- Persistent representation of a prior schema in the orbitofrontal cortex facilitates learning of a conflicting schema.Nature communications · 2026Article
- Affective schemas: Acquisition, updating, and inference.Emotion (Washington, D.C.) · 2026Article
- Episodic events are flexibly encoded in both integrated and separated neural representations.Nature communications · 2026Article
- Cognitive training shapes brain plasticity and schematic representations.Behavioral and brain functions : BBF · 2025Review
- Prefrontal Cortex Responses to Conflicting Information.Human brain mapping · 2025Article
- A Toaster in the Bathroom: Neural Correlates of Semantic Construction During Episodic Memory Recall.Human brain mapping · 2025Article
- Graph-like organization of non-spatial knowledge about social closeness in movie narratives.Scientific reports · 2025Article
- Propofol differentially modulates the consolidation of schema-related and -unrelated memory.iScience · 2025Article
- The Hippocampus Rapidly Integrates Sequence Representations During Novel Multistep Predictions.bioRxiv : the preprint server for biology · 2025Article
- Article
- Functional imaging of hippocampal layers using VASO and BOLD on the Next Generation (NexGen) 7T Scanner.bioRxiv : the preprint server for biology · 2025Article
- Music-evoked reactivation during continuous perception is associated with enhanced subsequent recall of naturalistic events.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Memory transformation is increasingly acknowledged in theoretical accounts of systems consolidation, yet how memory quality and neural representation change over time and how schemas influence this process remains unclear. We examined the behavioral quality and neural representation of schema-congruent and incongruent object-scene pairs retrieved across 10-minutes and 72-hours using fMRI. When a congruent schema was available, memory became coarser over time, aided by post-encoding coupling between the anterior hippocampus and medial prefrontal cortex (mPFC). Only schema-congruent representations were integrated in the mPFC over time, and were organized according to schematic context. In the hippocampus, pattern similarity changed across 72-hours such that the posterior hippocampus represented specific details and the anterior hippocampus represented the general context of specific memories, irrespective of congruency. Our findings suggest schemas are used as a scaffold to facilitate neocortical integration of congruent information, and illustrate evolution in hippocampal organization of detailed contextual memory over time.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.