Evidence map›Paper›PMID 36184436›Full record

ReviewJournal of the American Society of Cytopathology

Molecular testing of cytology specimens: overview of assay selection with focus on lung, salivary gland, and thyroid testing.

Paul A VanderLaan, Sinchita Roy-Chowdhuri, Christopher C Griffith, Vivian L Weiss, Christine N Booth

Open access · greenAbstract readReview
In one paragraph

Review in Journal of the American Society of Cytopathology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Paul A VanderLaanDepartment of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Sinchita Roy-ChowdhuriDepartment of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas.
Christopher C GriffithDepartment of Pathology, Cleveland Clinic, Cleveland, Ohio.
Vivian L WeissDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee.
Christine N BoothDepartment of Pathology, Cleveland Clinic, Cleveland, Ohio. Electronic address: boothc1@ccf.org.
Cleveland Clinic · USBeth Israel Deaconess Medical Center · USThe University of Texas MD Anderson Cancer Center · USVanderbilt University Medical Center · US

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
The role of Wnt signaling in aggressive thyroid carcinomaK08CA240901 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WEISS, VIVIAN LEE · 2020 to 2024
$1.1M
NCI NIH HHS K08 CA240901NCI NIH HHS K12 CA090625
6 · The paper itself

Abstract

Ancillary and molecular testing of cytopathology specimens has emerged as a reliable and useful tool to provide diagnostic information and treatment-related biomarker status for the management of cancer patients. The cytology specimens obtained through minimally invasive means have proven suitable testing substrates for a variety of ancillary tests, including immunohistochemistry, fluorescence in situ hybridization, as well as polymerase chain reaction and next generation sequencing molecular techniques. By focusing specifically on the cytology specimen, this review provides an overview of basic testing considerations and assay selection in addition to updates on the ancillary testing of cytologic tumor specimens from the lung, salivary gland, and thyroid.

Indexed as

Salivary GlandsThyroid GlandHumansIn Situ Hybridization, FluorescenceLungMolecular Diagnostic TechniquesCytologyFISHLungMolecular testingNext generation sequencingSalivary glandThyroid

Identifiers

PMID36184436
PMCPMC10225070
OpenAlexW4293859565

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.