Evidence map›Paper›PMID 36184235›Full record

ArticleClinical nutrition ESPEN2022

Machine learning approach for automated predicting of COVID-19 severity based on clinical and paraclinical characteristics: Serum levels of zinc, calcium, and vitamin D.

Azam Jahangirimehr, Elham Abdolahi Shahvali, Seyed Masoud Rezaeijo, Azam Khalighi, Azam Honarmandpour, Fateme Honarmandpour, Mostafa Labibzadeh, Nasrin Bahmanyari, Sahel Heydarheydari

Abstract read
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Article in Clinical nutrition ESPEN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Azam JahangirimehrShoushtar Faculty of Medical Sciences, Shoushtar, Iran. Electronic address: a.jahangirimehr@gmail.com.
Elham Abdolahi ShahvaliDepartment of Nursing, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran. Electronic address: eabdolahi31@yahoo.com.
Seyed Masoud RezaeijoDepartment of Medical Physics, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran. Electronic address: rezaei-sm@ajums.ac.ir.
Azam KhalighiKhatam Al-Anbia Hospital, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran. Electronic address: khalighiazam@gmail.com.
Azam HonarmandpourDepartment of Midwifery, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran. Electronic address: honarmandpour.a@gmail.com.
Fateme HonarmandpourKhatam Al-Anbia Hospital, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran. Electronic address: Amirmasuood439@gmail.com.
Mostafa LabibzadehShoushtar Faculty of Medical Sciences, Shoushtar, Iran. Electronic address: mlabibzadeh@yahoo.com.
Nasrin BahmanyariShoushtar Faculty of Medical Sciences, Shoushtar, Iran. Electronic address: n.bahmanyari18@gmail.com.
Sahel HeydarheydariDepartment of Radiology Technology, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran. Electronic address: sheydari7@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

aimsConsidering that no standard therapy has yet been found for the novel coronavirus disease (COVID-19), identifying severe cases as early as possible, and such that treatment procedures can be escalated seems necessary. Hence, the present study aimed to develop a machine learning (ML) approach for automated severity assessment of COVID-19 based on clinical and paraclinical characteristics like serum levels of zinc, calcium, and vitamin D.

methodsIn this analytical cross-sectional study which was conducted from May 2020 to May 2021, clinical and paraclinical data sets of COVID-19-positive patients with known outcomes were investigated by combining statistical comparison and correlation methods with ML algorithms, including Decision Tree (DT), Random Forest (RF), and Support Vector Machine (SVM).

resultsOur work revealed that some patients' characteristics including age, gender, cardiovascular diseases as an underlying condition, and anorexia as disease symptoms, and also some parameters which are measurable in blood samples including FBS and serum levels of calcium are factors that can be considered in predicting COVID-19 severity. In this regard, we developed ML predictive models that indicated accuracy and precision scores >90% for disease severity prediction. The SVM algorithm indicated better results than other algorithms by having a precision of 95.5%, recall of 94%, F1 score of 94.8%, the accuracy of 95%, and AUC of 94%.

conclusionsOur results indicated that clinical and paraclinical features like calcium serum levels can be used for automated severity assessment of COVID-19.

Indexed as

CalciumCOVID-19Cross-Sectional StudiesHumansMachine LearningSeverity of Illness IndexVitamin DVitaminsZincCalciumVitamin DVitaminsZincAutomated predictionCOVID-19 severityMachine learning

Identifiers

PMID36184235
PMCPMC9339089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.