Evidence map›Paper›PMID 36183822›Full record

Observational studyJournal of affective disorders2023

Personality traits as predictors of OCD remission: A longitudinal study.

Clara Law, Snigdha Kamarsu, Immanuela C Obisie-Orlu, Gina M Belli, Maria Mancebo, Jane Eisen, Steven Rasmussen, Christina L Boisseau

Abstract readObservational Study
In one paragraph

Observational study in Journal of affective disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Clara LawDepartment of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Snigdha KamarsuDepartment of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Immanuela C Obisie-OrluDepartment of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Gina M BelliDepartment of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Maria ManceboPsychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Jane EisenDivision of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA, USA.
Steven RasmussenPsychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Christina L BoisseauDepartment of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address: christina.boisseau@northwestern.edu.
Northwestern University · USBrown University · USMcLean Hospital · US

Funding

Longitudinal Follow-Up Study of Obsessive Compulsive DisorderR01MH060218 · NIMH · BUTLER HOSPITAL (PROVIDENCE, RI) · PI RASMUSSEN, STEVEN A · 2001 to 2015
$6.3M
Phenomenology of Obsessive Compulsive Personality DisorderK23MH080221 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI PINTO, ANTHONY · 2008 to 2012
$925k
Development of a Behavioral Team Intervention for Obsessive Compulsive DisorderK23MH091032 · NIMH · BUTLER HOSPITAL (PROVIDENCE, RI) · PI MANCEBO, MARIA C. · 2010 to 2014
$922k
NIMH NIH HHS K23 MH080221NIMH NIH HHS K23 MH091032NIMH NIH HHS R01 MH060218
6 · The paper itself

Abstract

backgroundPersonality traits may confer vulnerability to psychopathology. However, few studies have examined the association between personality traits and obsessive-compulsive disorder (OCD) course. The present study investigates personality traits, OCD symptom severity, and illness duration as a predictor of OCD remission.

methods166 treatment-seeking adults with OCD, recruited as part of the Brown Longitudinal Obsessive-Compulsive Study, completed the NEO Five-Factor Inventory 3 (NEO-FFI) and were in episode for OCD at time of NEO-FFI completion. Participants were followed for up to 3 years.

resultsResults suggest individuals with OCD had a 21 % likelihood of reaching remission over the course of 3 years. Greater OCD symptom severity and longer illness duration were associated with a decreased likelihood of remission. Among the five factors of personality, only low extraversion was associated with a decreased rate of remission. Neuroticism, openness, agreeableness, and conscientiousness were not associated with remission. LIMITATIONS: As this was an observational study, treatment was not controlled precluding examination of treatment on course. Further, data collected on age of onset and symptom severity during follow up were retrospective and therefore are also subject to recall bias.

conclusionsOur findings provide preliminary support that personality traits are potential factors impacting course and symptom presentation. Future research is necessary to determine the mechanisms in which personality traits may influence the presentation and course of OCD.

Indexed as

Obsessive-Compulsive DisorderAdultHumansLongitudinal StudiesPersonalityPersonality DisordersPersonality InventoryRetrospective StudiesLongitudinal studyObsessive-compulsive disorderPersonality traitsRemission

Identifiers

PMID36183822
PMCPMC13557202
OpenAlexW4297984454

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.