Evidence map›Paper›PMID 36183120›Full record

ArticleImplementation science communications2022

Key population-led community-based same-day antiretroviral therapy (CB-SDART) initiation hub in Bangkok, Thailand: a protocol for a hybrid type 3 implementation trial.

Sita Lujintanon, Sorawit Amatavete, Supanat Thitipatarakorn, Thanyawee Puthanakit, Wipaporn Natalie Songtaweesin, Tanachai Chaisalee, Surang Janyam, Nittaya Phanuphak, Reshmie A Ramautarsing

Abstract read
In one paragraph

Article in Implementation science communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sita LujintanonDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD, 21205, USA. slujint1@jhu.edu.ORCID http://orcid.org/0000-0001-5380-2013
Sorawit AmataveteInstitute of HIV Research and Innovation (IHRI), Bangkok, Thailand.
Supanat ThitipatarakornInstitute of HIV Research and Innovation (IHRI), Bangkok, Thailand.
Thanyawee PuthanakitDivision of Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University (PIDCU), Bangkok, Thailand.
Wipaporn Natalie SongtaweesinDivision of Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University (PIDCU), Bangkok, Thailand.
Tanachai ChaisaleeRainbow Sky Association of Thailand (RSAT), Bangkok, Thailand.
Surang JanyamService Workers In Group Foundation (SWING), Bangkok, Thailand.
Nittaya PhanuphakInstitute of HIV Research and Innovation (IHRI), Bangkok, Thailand.
Reshmie A RamautarsingInstitute of HIV Research and Innovation (IHRI), Bangkok, Thailand.

Funding

Association of Providers of AIDS Care 2021-ISG-Y1-10008United States Agency for International Development AID-OAA-A-14-0045
6 · The paper itself

Abstract

backgroundSame-day antiretroviral therapy (SDART) initiation, in which people living with HIV (PLHIV) who are antiretroviral therapy (ART)-naïve, willing, and clinically eligible start ART on the same day of HIV diagnosis, has been implemented in several healthcare facilities in Thailand since 2017. This evidence-based practice has demonstrated increased ART uptake, virologic suppression, and retention in care. However, linkage to care gaps exist in community-based organizations (CBOs) in Bangkok whereby as much as 20% of key populations (KP), mainly men who have sex with men and transgender women, living with HIV were lost to follow-up pre-ART initiation. To increase access to and uptake of ART among these populations, this study proposes that trained KP lay providers should lead community-based ART (CB-SDART) initiation service. This protocol describes the combined use of the Proctor's implementation outcome framework and the Consolidated Framework for Implementation Research to guide and evaluate the CB-SDART implementation.

methodsThis study follows the hybrid design type 3: it is an implementation trial that secondarily assesses service and client outcomes by comparative interrupted time series analysis. Five strategies have been formulated to meet three implementation outcomes (i.e., feasibility, fidelity, and sustainability): (1) developing stakeholder relationships by engaging the CBO leaderships, (2) training and educating KP lay providers, (3) adapting and tailoring SDART to CBO-specific context, (4) using evaluative and iterative strategies to assess adherence to standard operating procedures, and (5) developing stakeholder relationships by engaging external stakeholders. Teleconsultation with physicians and ART home delivery will be integrated as another ART initiation option for clients and allow service provision during the COVID-19 pandemic. A mixed-method assessment will be conducted on key stakeholders and PLHIV diagnosed at two implementing CBOs, Rainbow Sky Association of Thailand and Service Workers in Group Foundation, in Bangkok, Thailand. DISCUSSION: This implementation research may be the first to provide robust data at the implementation, service, and client levels to inform how to successfully task-shift SDART initiation service to trained KP lay providers and facilitate the expansion of CB-SDART in the future.

trial registrationThis trial was registered with the Thai Clinical Trial Registry as TCTR20210709004 on July 9, 2021.

Indexed as

Antiretroviral therapy initiationCommunity-based serviceHIVImplementation researchKey populationMen who have sex with menTelehealthTransgender women

Identifiers

PMID36183120
PMCPMC9526529

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.