Evidence map›Paper›PMID 36183115›Full record

ArticleLaboratory animal research2022

Comparison of young male mice of two different strains (C57BL/6J and the hybrid B6129SF1/J) in selected behavior tests: a small scale study.

Kristine Eraker Aasland Hansen, Alexandra M Hudecová, Fred Haugen, Eystein Skjerve, Erik Ropstad, Karin E Zimmer

Abstract read
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In one paragraph

Article in Laboratory animal research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristine Eraker Aasland HansenSection for Experimental Biomedicine, Department of Production Animal Clinical Sciences, Norwegian University of Life Sciences, Ås, Norway. kristine.hansen@nmbu.no.ORCID http://orcid.org/0000-0001-5946-4043
Alexandra M HudecováEnvironmental Chemistry Department, Norwegian Institute for Air Research, Ås, Norway.
Fred HaugenDivision of Work Physiology, National Institute of Occupational Health, Oslo, Norway.
Eystein SkjerveSection for Animal Welfare, Department of Production Animal Clinical Sciences, Norwegian University of Life Sciences, Ås, Norway.
Erik RopstadSection for Stationary Clinics, Department of Production Animal Clinical Sciences, Norwegian University of Life Sciences, Ås, Norway.
Karin E ZimmerPhysiology Unit, Department of Preclinical Sciences and Pathology, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.

Funding

Norwegian Research Council 213076/H10
6 · The paper itself

Abstract

backgroundAll mouse strains are different, before choosing a strain for a large study, a small scale study should be done. In this study, we compared young males of two mouse strains, C57BL/6J and the hybrid B6129SF1/J, and gained knowledge on their performance in three different behavioral tests; open field (OF) test, Barnes maze (BM) test and a restraint stress test.

resultsWe found that the young males of the C57BL/6J strain spent more time moving in the OF. In the BM, the hybrid covered less ground before reaching the goal box during the first three sessions, than the C57BL/6J. The hybrid left more fecal pellets than C57BL/6J both in OF and BM. During the stress test, the C57BL/6J had a lower corticosterone response than the hybrid.

conclusionsOur findings indicate that the C57BL/6J has a presumably higher locomotor activity and/or explorative behavior than the hybrid, while the hybrid appeared more sensitive to stress.

Indexed as

Barnes maze testBehavior testC57BL/6JHybrid B6129SF1/JMouse strainOpen field testStress test

Identifiers

PMID36183115
PMCPMC9526948

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.