Evidence map›Paper›PMID 36183050›Full record

ArticleChild psychiatry and human development2024

Effectiveness of Psychotropic Medications in Children with Prenatal Alcohol and Drug Exposures: A Case Series and Model of Care.

Gaby J Ritfeld, Julie A Kable, Jennifer E Holton, Claire D Coles

Abstract read
PubMed Publisher
In one paragraph

Article in Child psychiatry and human development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Fetal alcohol spectrum disorders.Nature reviews. Disease primers · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gaby J RitfeldBarrow Neurological Institute at Phoenix Children's Hospital, 1919 E Thomas Rd, Phoenix, AZ, 85016, USA. gritfeld@phoenixchildrens.com.ORCID http://orcid.org/0000-0002-7024-5041
Julie A KableDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Jennifer E HoltonDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Claire D ColesDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.

Funding

Fetal Alcohol Spectrum Disorders in Adults: Health and NeurobehaviorU01AA026108 · NIAAA · EMORY UNIVERSITY · PI Tamara Sonia Bodnar, Claire D. Coles · 2017 to 2026
$3.9M
Prenatal Alcohol Exposure: Adult NeurocognitionR01AA014373 · NIAAA · EMORY UNIVERSITY · PI COLES, CLAIRE D · 2003 to 2007
$2.8M
NIAAA NIH HHS 3U01AA026108-04S1ANIAAA NIH HHS R01 AA014373
6 · The paper itself

Abstract

Fetal Alcohol Spectrum Disorders affect up to 5% of the population, with additional children affected by prenatal drug exposures. The majority of these children display symptoms of ADHD and poor emotional dysregulation, a common reason for seeking psychiatric care. However, high prevalence of comorbid look-alike symptoms and limited availability of evidence-based treatments complicates psychiatric decision making in this population. The goal of the current study is to report on the effectiveness of psychotropic medications in a case series of 16 individuals with prenatal alcohol/drug exposure and propose a model for psychiatric care for this population. In addition to traditional subjective reports, an objective continuous performance test (T.O.V.A.®) was used to aid with guiding treatment. We found that T.O.V.A.®-scores improved on average from - 6.5 to - 2.9 with our psychiatric approach (p = 0.03). T.O.V.A.®-measurements were helpful in differentiating ADHD symptoms from comorbid symptoms and to guide decision-making on starting and changing medications.

Indexed as

Attention Deficit Disorder with HyperactivityFetal Alcohol Spectrum DisordersPrenatal Exposure Delayed EffectsPsychotropic DrugsAdolescentChildComorbidityFemaleHumansMalePregnancyPsychotropic DrugsFetal Alcohol Spectrum DisorderModel of carePrenatal substance exposurePsychotropic medication

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.