Evidence map›Paper›PMID 36181777›Full record

ReviewFrontiers in neuroendocrinology2022

Combined oral contraceptive use and risk for binge eating in women: Potential gene × hormone interactions.

Kelly L Klump, Alaina M Di Dio

Open access · greenAbstract readReview
In one paragraph

Review in Frontiers in neuroendocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Beyond Birth Control: The Neuroscience of Hormonal Contraceptives.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kelly L KlumpDepartment of Psychology, Michigan State University, 316 Physics Road - Room 107B, East Lansing, MI 48824-1116, United States. Electronic address: klump@msu.edu.
Alaina M Di DioDepartment of Psychology, Oberlin College, South Hall, 121 Elm Street, Oberlin, OH 44074, United States.
Michigan State University · USOberlin College · US

Funding

A Twin Study of exogenous hormone exposure and risk for binge eatingR01MH111715 · NIMH · MICHIGAN STATE UNIVERSITY · PI KLUMP, KELLY L · 2017 to 2021
$4.0M
NIMH NIH HHS R01 MH111715
6 · The paper itself

Abstract

Extant animal and human data suggest endogenous ovarian hormones increase risk for binge eating in females, possibly via gene × hormone interactions and hormonally induced increases in genetic influences. Approximately 85 % of women will take combined oral contraceptives (COCs) that mimic the riskiest hormonal milieu for binge eating (i.e., post-ovulation when both estrogen and progesterone are present). The purpose of this narrative review is to synthesize findings of binge eating risk in COC users. Few studies have been conducted, but results suggest that COCs may increase risk for binge eating and related phenotypes (e.g., craving for sweets), particularly in genetically vulnerable women. Larger, more systematic human and animal studies of COCs and binge eating are needed. The goal of this work should be to advance personalized medicine by identifying the extent of COC risk as well as the role of gene × hormone interactions in susceptibility.

Indexed as

Binge-Eating DisorderContraceptives, Oral, CombinedAnimalsEstrogensFemaleHumansProgesteroneContraceptives, Oral, CombinedEstrogensProgesteroneAnimal studiesBinge eatingCombined oral contraceptivesEstrogenGene × hormone interactionsHormonal contraceptivesProgesterone

Identifiers

PMID36181777
PMCPMC9679583
OpenAlexW4297535699

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.