ArticleMolecular biology and evolution2022
sstar: A Python Package for Detecting Archaic Introgression from Population Genetic Data with S.
Article in Molecular biology and evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Recent advances in methods to characterize archaic introgression in modern humans.Genome research · 2026Review
- A curated dataset of great ape genome diversity.Scientific data · 2025Article
- Biogeographic Perspectives on Human Genetic Diversification.Molecular biology and evolution · 2024Article
- Harnessing deep learning for population genetic inference.Nature reviews. Genetics · 2024Review
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Abstract
S* is a widely used statistic for detecting archaic admixture from population genetic data. Previous studies used freezing-archer to apply S*, which is only directly applicable to the specific case of Neanderthal and Denisovan introgression in Papuans. Here, we implemented sstar for a more general purpose. Compared with several tools, including SPrime, SkovHMM, and ArchaicSeeker2.0, for detecting introgressed fragments with simulations, our results suggest that sstar is robust to differences in demographic models, including ghost introgression and two-source introgression. We believe sstar will be a useful tool for detecting introgressed fragments in various scenarios and in non-human species.
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