Article in Journal of medical virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 0 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
5 authors at 2 institutions in 1 country.
Antonio Solis-LealHost-Pathogen Interaction Program & Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0002-5063-3266
Ann-Marie MayTulane National Primate Research Center, Covington, Louisiana, USA.
Mahesh MohanHost-Pathogen Interaction Program & Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Jason P DufourTulane National Primate Research Center, Covington, Louisiana, USA.
Binhua LingHost-Pathogen Interaction Program & Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Texas Biomedical Research Institute · USTulane University · US
Funding
Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Viral Testing CoreU42OD010442 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI SHELLEY A COLE · 2012 to 2026
$35.6M
Viral Testing CoreU42OD024282 · OD · TULANE UNIVERSITY OF LOUISIANA · PI KASI E RUSSELL-LODRIGUE · 2017 to 2026
$25.7M
Brain myeloid cell-targeted multiplexed gene editing for SIV/HIV eradicationR01MH130193 · NIMH · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Wenhui Hu, Binhua Julie Ling · 2022 to 2026
$4.0M
CD4 T cell-targeted nanoparticle in vivo delivery of CRISPR/Cas9 genome editors for HIV cureR01AI145034 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI HU, WENHUI · 2019 to 2023
$3.8M
Eradication of latent SIV from the CNSR01NS104016 · NINDS · TULANE UNIVERSITY OF LOUISIANA · PI LING, BINHUA "JULIE", MACLEAN, ANDREW G · 2017 to 2021
$3.7M
CNS Myeloid Cells as SIV Reservoirs: Persistent Infection and ReboundR01MH116844 · NIMH · TULANE UNIVERSITY OF LOUISIANA · PI LING, BINHUA "JULIE" · 2018 to 2022
$3.4M
Identification and eradication of HIV tissue reservoirs in a relevant animal modeR01AI093307 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI LING, BINHUA "JULIE" · 2011 to 2013
The gut is a major reservoir in HIV-infected individuals on antiretroviral therapy (ART) and in long-term non-progressors (LTNPs). Whether ART reduces gut infection and reservoirs in LTNPs is unknown. Herein, SIV-infected LTNP Rhesus macaques were treated with short- or long-term ART, and SIV envelope gp120 sequences obtained from single genome amplification were analyzed before and after ART in peripheral blood and the intestine. Although ART does not eliminate SIV in these LTNPs, a longer ART period dramatically reduces SIV infection in the gut. This study highlights the importance of long-term ART in LTNPs to minimize gut infection and prolong remission.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Duration of antiretroviral therapy impacts the degree of residual SIV infection in the gut in long-term non-progressing Chinese rhesus macaques. · full record | OpenQuestion