Evidence map›Paper›PMID 36181315›Full record

ArticleJournal of clinical nursing2024

The other COVID-19 survivors: Timing, duration, and health impact of post-acute sequelae of SARS-CoV-2 infection.

Natalie Lambert, Survivor Corps, Sarah A El-Azab, Nathan S Ramrakhiani, Anthony Barisano, Lu Yu, Kaitlyn Taylor, Álvaro Esperança, Christian Mendiola, Charles A Downs and 6 more

Abstract read
In one paragraph

Article in Journal of clinical nursing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  14. Impact of Post-Acute Sequelae of COVID-19 on Lives of Patients Post-Intensive Care Unit Discharge: A Cross-Sectional Study.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Natalie LambertDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0002-4820-2619
Survivor Corps
Sarah A El-AzabDepartment of Health Management and Policy, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0003-4435-4700
Nathan S RamrakhianiBrown University, Providence, Rhode Island, USA.
Anthony BarisanoBrown University, Providence, Rhode Island, USA.
Lu YuSchool of Labor and Employment Relations, University of Illinois at Urbana-Champaign, Champaign, Illinois, USA.
Kaitlyn TaylorLambert Health Lab, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Álvaro EsperançaPurdue School of Engineering and Technology, Indiana University Purdue University Indianapolis, Indianapolis, Indiana, USA.
Christian MendiolaPurdue School of Engineering and Technology, Indiana University Purdue University Indianapolis, Indianapolis, Indiana, USA.
Charles A DownsSchool of Nursing & Health Studies, University of Miami, Coral Gables, Florida, USA.
Heather L AbrahimSue & Bill Gross School of Nursing, University of California Irvine, Irvine, California, USA.
Thomas HughesSue & Bill Gross School of Nursing, University of California Irvine, Irvine, California, USA.
Amir M RahmaniSue & Bill Gross School of Nursing, University of California Irvine, Irvine, California, USA.
Jessica L BorelliDepartment of Psychological Science, University of California Irvine, Irvine, California, USA.
Rana ChakrabortyDivision of Infectious Disease, Department of Pediatrics and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Melissa D PintoSue & Bill Gross School of Nursing, University of California Irvine, Irvine, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS AND

objectivesTo determine the frequency, timing, and duration of post-acute sequelae of SARS-CoV-2 infection (PASC) and their impact on health and function.

backgroundPost-acute sequelae of SARS-CoV-2 infection is an emerging major public health problem that is poorly understood and has no current treatment or cure. PASC is a new syndrome that has yet to be fully clinically characterised.

designDescriptive cross-sectional survey (n = 5163) was conducted from online COVID-19 survivor support groups who reported symptoms for more than 21 days following SARS-CoV-2 infection.

methodsParticipants reported background demographics and the date and method of their covid diagnosis, as well as all symptoms experienced since onset of covid in terms of the symptom start date, duration, and Likert scales measuring three symptom-specific health impacts: pain and discomfort, work impairment, and social impairment. Descriptive statistics and measures of central tendencies were computed for participant demographics and symptom data.

resultsParticipants reported experiencing a mean of 21 symptoms (range 1-93); fatigue (79.0%), headache (55.3%), shortness of breath (55.3%) and difficulty concentrating (53.6%) were the most common. Symptoms often remitted and relapsed for extended periods of time (duration M = 112 days), longest lasting symptoms included the inability to exercise (M = 106.5 days), fatigue (M = 101.7 days) and difficulty concentrating, associated with memory impairment (M = 101.1 days). Participants reported extreme pressure at the base of the head, syncope, sharp or sudden chest pain, and "brain pressure" among the most distressing and impacting daily life.

conclusionsPost-acute sequelae of SARS-CoV-2 infection can be characterised by a wide range of symptoms, many of which cause moderate-to-severe distress and can hinder survivors' overall well-being. RELEVANCE TO CLINICAL PRACTICE: This study advances our understanding of the symptoms of PASC and their health impacts.

Indexed as

Acute PainCOVID-19Cross-Sectional StudiesDisease ProgressionFatigueHumansPost-Acute COVID-19 SyndromeSARS-CoV-2Survivorschronic diseaseCOVID-19symptomsymptom burden

Identifiers

PMID36181315
PMCPMC9538514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.