ArticleEye and vision (London, England)2022
Age- and sex-related differences in the retinal capillary plexus in healthy Chinese adults.
Article in Eye and vision (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 19 citations in OpenAlex.
- Reference Percentiles for Macular Vessel Density by OCT Angiography and Their Association with Systemic Diseases in Chinese Adults.Ophthalmology science · 2026Article
- Diabetes May Modulate the Association Between Age and Optical Coherence Tomography Angiography Parameters: A Serial, Cross-Sectional Study.Journal of personalized medicine · 2026Article
- Vascular Changes in the Macula and Peripapillary Regions Using Optical Coherence Tomography Angiography in Migraine with Aura and Migraine Without Aura.Journal of clinical medicine · 2026Article
- Association of Remnant Cholesterol With the Retinal Capillary Plexus.Translational vision science & technology · 2026Article
- Quantitative assessment of age-related retinal and choriocapillaris blood flow changes in a healthy Korean population using optical coherence tomography angiography.Scientific reports · 2026Article
- Diabetic Retinopathy (DR) nomogram construction based on optical coherence tomography angiography parameters: a preliminary exploration of DR prediction.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- AI-Based Ocular Age Estimation from Combined OCT and OCTA Metrics: Decade-Stratified Normative Modelling in Healthy Eyes - A Pilot Study [Letter].Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Association between gamma-glutamyl transferase levels and the retinal age gap.Frontiers in physiology · 2025Article
- AI-Based Ocular Age Estimation from Combined OCT and OCTA Metrics: Decade-Stratified Normative Modelling in Healthy Eyes - a Pilot Study.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Identification of diabetic retinopathy classification using machine learning algorithms on clinical data and optical coherence tomography angiography.Eye (London, England) · 2024Observational
- The effects of time restricted feeding on age-related changes in the mouse retina.Experimental gerontology · 2024Article
- Estimation of foveal avascular zone area from a B-scan OCT image using machine learning algorithms.PloS one · 2024Article
- Association of Male Sex and Microvascular Alterations on Optical Coherence Tomography Angiography in Diabetes.Translational vision science & technology · 2023Article
- Macular vessel density in the superficial plexus is not associated to cerebrospinal fluid core biomarkers for Alzheimer's disease in individuals with mild cognitive impairment: The NORFACE cohort.Frontiers in neuroscience · 2023Article
- Associations of macular microvascular parameters with cerebral small vessel disease in rural older adults: A population-based OCT angiography study.Frontiers in neurology · 2023Article
- Construction and Interpretability of a Multimodal Deep Learning Model of Electronystagmography-Optical Coherence Tomography Angiography for Early Screening of Alzheimer's Disease.American journal of Alzheimer's disease and other dementiasArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundTo assess age- and sex-related changes in the superficial retinal capillary plexus (SCP) and deep retinal capillary plexus (DCP) in healthy Chinese adults.
methodsIn this cross-sectional study, all data were derived from the community-based Jidong Eye Cohort Study. Participants underwent optical coherence tomography angiography (OCTA) and other ocular and systemic examinations. The vessel densities of the whole measured area, parafovea, and four quadrants in the SCP and DCP were measured.
resultsWe recruited 1036 eyes of 1036 healthy participants; the mean age was 40.4 ± 9.8 years, and 449 (43.3%) participants were males. The SCP and DCP vessel densities in all regions, except for temporal and nasal regions in the SCP, non-linearly decreased with age. The DCP vessel densities began to decrease at approximately 35 years of age, while the SCP vessel densities began to decrease at approximately 40 years of age. The DCP vessel densities decreased more rapidly than the SCP vessel densities at 35-50 years of age. The DCP vessel densities remained stable or slightly decreased after the age of 50 years in females, while those decreased linearly in most regions in males.
conclusionsThe retinal vessel density decreased earlier and more rapidly in the DCP than in the SCP, and the effect of aging on the DCP vessel density was sex-dependent. Our findings suggest that age and sex should be considered when interpreting clinical quantitative OCTA data.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.