Evidence map›Paper›PMID 36180829›Full record

ArticleBMC infectious diseases2022

Chromosomal coharboring of bla

Yusuke Miyazato, Noriko Iwamoto, Masaru Usui, Toyotaka Sato, Tohru Miyoshi-Akiyama, Maki Nagashima, Kazuhisa Mezaki, Kayoko Hayakawa, Norio Ohmagari

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yusuke MiyazatoDisease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan. ymiyazato@hosp.ncgm.go.jp.
Noriko IwamotoDisease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan. nkinoshita@hosp.ncgm.go.jp.ORCID http://orcid.org/0000-0001-5471-7363
Masaru UsuiLaboratory of Food Microbiology and Food Safety, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
Toyotaka SatoLaboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Tohru Miyoshi-AkiyamaPathogenic Microbe Laboratory, National Center for Global Health and Medicine, Tokyo, Japan.
Maki NagashimaDisease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Kazuhisa MezakiDepartment of Clinical Laboratory, National Center for Global Health and Medicine, Tokyo, Japan.
Kayoko HayakawaDisease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
Norio OhmagariDisease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.
National Center for Global Health and Medicine · JPHokkaido University · JPRakuno Gakuen University · JP

Funding

Japan Agency for Medical Research and Development 20jk0210004h0001Japan Agency for Medical Research and Development 21ak0101118h9903
6 · The paper itself

Abstract

backgroundPolymyxin E (colistin) is a last-resort antibiotic to treat infections caused by carbapenemase-producing Enterobacteriaceae (CPE). However, reports of CPEs resistant to colistin have been increasing, and the mcr genes are emerging as resistance mechanisms. Among them, plasmid-mediate mcr-9 is known to be associated with colistin resistance, whereas reports on chromosomal mcr-9 and its association with colistin resistance in humans are few. CASE PRESENTATION: We identified Enterobacter asburiae harboring mcr-9 and bla

conclusionOur case report showed that mcr-9 can be present not only on plasmids but also on the chromosome in E. asburiae, and that the presence of mcr-9 on its chromosome may influence its susceptibility to colistin.

Indexed as

EmpyemaEscherichia coli ProteinsAnti-Bacterial AgentsChromosomesColistinDrug Resistance, BacterialEnterobacterHumansJapanMicrobial Sensitivity TestsPlasmidsAnti-Bacterial AgentsColistinEscherichia coli ProteinsBla IMPCase reportChromosomeHeteroresistancemcr-9

Identifiers

PMID36180829
PMCPMC9523918
OpenAlexW4298143002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.