Evidence map›Paper›PMID 36179268›Full record

ArticleBlood2023

Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions.

Georgina L Ryland, Masayuki Umeda, Linda Holmfeldt, Sören Lehmann, Morten Krogh Herlin, Jing Ma, Mahsa Khanlari, Jeffrey E Rubnitz, Rhonda E Ries, Hansen J Kosasih and 11 more

Abstract readComment
In one paragraph

Article in Blood, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Georgina L RylandDepartment of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.ORCID 0000-0002-4990-0961
Masayuki UmedaDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN.
Linda HolmfeldtDepartment of Immunology, Genetics, and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-4140-3423
Sören LehmannDepartment of Hematology, Karolinska University Hospital, Stockholm, Sweden.
Morten Krogh HerlinDepartment of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-7179-4643
Jing MaDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN.
Mahsa KhanlariDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN.
Jeffrey E RubnitzDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0001-9885-3527
Rhonda E RiesClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Hansen J KosasihMurdoch Children's Research Institute, Parkville, VIC, Australia.ORCID 0000-0002-0428-6195
Paul G EkertSir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia.
Hwee Ngee GohDepartment of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Ing S TiongDepartment of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.ORCID 0000-0001-7417-4343
Sean M GrimmondCentre for Cancer Research, University of Melbourne, Parkville, VIC, Australia.ORCID 0000-0002-8102-7998
Claudia HaferlachMunich Leukemia Laboratory, Munich, Germany.
Ryan B DayDivision of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.ORCID 0000-0002-4376-4663
Timothy J LeyDivision of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO.ORCID 0000-0002-9913-0520
Soheil MeshinchiClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Xiaotu MaDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN.
Piers BlomberyDepartment of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Jeffery M KlcoDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN.

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Molecular Pathogenesis of Acute Myeloid LeukemiaR35CA197561 · NCI · WASHINGTON UNIVERSITY · PI Timothy J. Ley · 2015 to 2026
$11.0M
NCI NIH HHS P30 CA021765NCI NIH HHS R35 CA197561
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leukemia, Myeloid, AcuteCore Binding Factor beta SubunitHumansOncogene Proteins, FusionCBFB protein, humanCore Binding Factor beta SubunitOncogene Proteins, Fusion

Identifiers

PMID36179268
PMCPMC10273080

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.