ArticlePloS one2022
Influenza vaccine coverage and factors associated with non-vaccination among adults at high risk for severe outcomes: An analysis of the Canadian Longitudinal Study on Aging.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- The effect of alcohol, tobacco, and other drug use on vaccine acceptance, uptake, and adherence: a systematic review.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024Pooled it
- Review
- What Drives Influenza Vaccination in People with Diabetes? Evidence from the National Health Surveys of 2020 and 2023 in Spain.Epidemiologia (Basel, Switzerland) · 2026Article
- Vaccination Strategies Against Respiratory Pathogens in the Adult Population: A Narrative Review.Vaccines · 2026Review
- Association of socio-economic and clinical factors with influenza vaccination uptake in high-risk individuals: an Italian retrospective cohort study, 2019-2023.International journal of health geographics · 2025Article
- Coverage of the influenza and pneumococcal vaccinations among immigrant and non-immigrant older adults in Canada: a cross-sectional analysis of data from the Canadian Longitudinal Study on Aging (CLSA).BMC public health · 2025Article
- Characterizing influenza vaccine coverage and factors associated with missed vaccination among adults from 2018 to 2021: an analysis of the Canadian Longitudinal Study on Aging (CLSA) follow-up 2.BMC public health · 2025Article
- Explaining seasonality increases perceived effectiveness of influenza vaccination: An experimental study.British journal of health psychology · 2025Article
- Influenza vaccination uptake among at-risk patients in Switzerland-The potential of national claims data for surveillance.Influenza and other respiratory viruses · 2023Article
- Perspectives of Older Adults on COVID-19 and Influenza Vaccination in Ontario, Canada.Journal of primary care & community healthArticle
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundInfluenza vaccination is recommended in Canada for older adults and those with underlying health conditions due to their increased risk of severe outcomes. Further research is needed to identify who within these groups is not receiving influenza vaccine to identify opportunities to increase coverage.
objectivesWe aimed to 1) estimate influenza non-vaccination prevalence and 2) assess factors associated with non-vaccination among Canadian adults aged ≥65 and adults aged 46-64 with ≥1 chronic medical condition (CMC) due to their high risk of severe influenza outcomes.
methodsWe conducted a secondary analysis of cross-sectional data collected from 2015-2018 among participants of the Canadian Longitudinal Study on Aging. For both groups of interest, we estimated non-vaccination prevalence and used logistic regression models to identify factors associated with non-vaccination. We report adjusted odds ratios and 95% confidence intervals for the investigated variables.
resultsOverall, 29.5% (95% CI: 28.9%, 30.1%) of the 23,226 participants aged ≥65 years and 50.4% (95% CI: 49.4%, 51.3%) of the 11,250 participants aged 46-64 years with ≥1 CMC reported not receiving an influenza vaccination in the past 12 months. For both groups, lack of recent contact with a family doctor and current smoking were independently associated with non-vaccination. DISCUSSION: Influenza vaccination helps prevent severe influenza outcomes. Yet, half of adults aged 46-64 years with ≥1 CMC and more than one-quarter of all adults aged ≥65 years did not receive a recommended influenza vaccine in the year prior to the survey. Innovation in vaccination campaigns for routinely recommended vaccines, especially among those without annual family doctor visits, may improve coverage.
conclusionInfluenza vaccination coverage among Canadian adults aged 46-64 years with ≥1 CMC and adults aged ≥65 years remains suboptimal. Vaccination campaigns targeting those at high risk of severe outcomes without routine physician engagement should be evaluated to improve uptake.
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