Evidence map›Paper›PMID 36178720›Full record

SynthesisJournal of medical Internet research2022

Enabling Early Obstructive Sleep Apnea Diagnosis With Machine Learning: Systematic Review.

Daniela Ferreira-Santos, Pedro Amorim, Tiago Silva Martins, Matilde Monteiro-Soares, Pedro Pereira Rodrigues

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Journal of medical Internet research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 4 pooled it
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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  16. A novel machine learning model for screening the risk of obstructive sleep apnea using craniofacial photography with questionnaires.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daniela Ferreira-SantosDepartment of Community Medicine, Information and Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.ORCID 0000-0002-0390-9944
Pedro AmorimDepartment of Community Medicine, Information and Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.ORCID 0000-0001-7466-4174
Tiago Silva MartinsCenter for Health Technology and Services Research, Porto, Portugal.ORCID 0000-0002-2718-7093
Matilde Monteiro-SoaresDepartment of Community Medicine, Information and Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.ORCID 0000-0002-4586-2910
Pedro Pereira RodriguesDepartment of Community Medicine, Information and Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.ORCID 0000-0001-7867-6682
Universidade do Porto · PTCentre for Health Technology and Services Research · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmerican Academy of Sleep Medicine guidelines suggest that clinical prediction algorithms can be used to screen patients with obstructive sleep apnea (OSA) without replacing polysomnography, the gold standard.

objectiveWe aimed to identify, gather, and analyze existing machine learning approaches that are being used for disease screening in adult patients with suspected OSA.

methodsWe searched the MEDLINE, Scopus, and ISI Web of Knowledge databases to evaluate the validity of different machine learning techniques, with polysomnography as the gold standard outcome measure and used the Prediction Model Risk of Bias Assessment Tool (Kleijnen Systematic Reviews Ltd) to assess risk of bias and applicability of each included study.

resultsOur search retrieved 5479 articles, of which 63 (1.15%) articles were included. We found 23 studies performing diagnostic model development alone, 26 with added internal validation, and 14 applying the clinical prediction algorithm to an independent sample (although not all reporting the most common discrimination metrics, sensitivity or specificity). Logistic regression was applied in 35 studies, linear regression in 16, support vector machine in 9, neural networks in 8, decision trees in 6, and Bayesian networks in 4. Random forest, discriminant analysis, classification and regression tree, and nomogram were each performed in 2 studies, whereas Pearson correlation, adaptive neuro-fuzzy inference system, artificial immune recognition system, genetic algorithm, supersparse linear integer models, and k-nearest neighbors algorithm were each performed in 1 study. The best area under the receiver operating curve was 0.98 (0.96-0.99) for age, waist circumference, Epworth Somnolence Scale score, and oxygen saturation as predictors in a logistic regression.

conclusionsAlthough high values were obtained, they still lacked external validation results in large cohorts and a standard OSA criteria definition.

trial registrationPROSPERO CRD42021221339; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=221339.

Indexed as

Sleep Apnea, ObstructiveAdultBayes TheoremHumansMachine LearningNeural Networks, ComputerPolysomnographymachine learningobstructive sleep apneapolysomnographysystematic review

Identifiers

PMID36178720
PMCPMC9568812
OpenAlexW4285814847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.