Evidence map›Paper›PMID 36178697›Full record

ArticleJAMA network open2022

Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children: A Modified Delphi Consensus Statement.

Stuart L Goldstein, Ayse Akcan-Arikan, Rashid Alobaidi, David J Askenazi, Sean M Bagshaw, Matthew Barhight, Erin Barreto, Benan Bayrakci, Orville N R Bignall, Erica Bjornstad and 38 more

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in JAMA network open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 4 pooled it
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 4 syntheses or guidelines pooled it, 141 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Acute kidney injury and subsequent risk of late-onset infection among extremely low gestational age newborns.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Trial
  6. Trial
  7. Trial
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Research progress on biomarkers for acute kidney injury in children.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  16. Kidney care at NICU discharge and follow-up recommendations for preterm infants<34 weeks.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  17. Article
  18. Review
  19. Article
  20. Nephrotoxicity and kidney outcomes in pediatric oncology patients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

48 authors at 20 institutions in 7 countries.

Stuart L GoldsteinCenter for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Ayse Akcan-ArikanDivision of Critical Care Medicine and Nephrology, Texas Children's Hospital, Baylor College of Medicine, Houston.
Rashid AlobaidiAlberta Health Sciences University, Edmonton, Alberta, Canada.
David J AskenaziChildren's Hospital Alabama, Birmingham.
Sean M BagshawAlberta Health Sciences University, Edmonton, Alberta, Canada.
Matthew BarhightAnn & Robert Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois.
Erin BarretoMayo Clinic, Rochester, Minnesota.
Benan BayrakciDepartment of Pediatric Intensive Care Medicine, Life Support Center, Hacettepe University, Ankara, Turkey.
Orville N R BignallNationwide Children's Hospital, The Ohio State University, Columbus.
Erica BjornstadChildren's Hospital Alabama, Birmingham.
Patrick D BrophyGolisano Children's Hospital, Rochester University Medical Center, Rochester, New York.
Rahul ChanchlaniMcMaster University, Hamilton, Ontario, Canada.
Jennifer R CharltonUniversity of Virginia, Charlottesville.
Andrea L ConroyRiley Children's Hospital, Indiana University, Bloomington.
Akash DeepKing's College London, London, United Kingdom.
Prasad DevarajanCenter for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Kristin DolanMercy Children's Hospital Kansas City, Kansas City, Missouri.
Dana Y FuhrmanChildren's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Katja M GistCenter for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Stephen M GorgaC.S. Mott Children's Hospital, University of Michigan, Ann Arbor.
Jason H GreenbergYale University Medical Center, New Haven, Connecticut.
Denise HassonCenter for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Emma Heydari UlrichAlberta Health Sciences University, Edmonton, Alberta, Canada.
Arpana IyengarSt John's Academy of Health Sciences, Bangalore, Karnataka, India.
Jennifer G JettonStead Family Children's Hospital, The University of Iowa, Iowa City.
Catherine KrawczeskiNationwide Children's Hospital, The Ohio State University, Columbus.
Leslie MeigsStead Family Children's Hospital, The University of Iowa, Iowa City.
Shina MenonSeattle Children's Hospital, Seattle, Washington.
Jolyn MorganCenter for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Catherine J MorganAlberta Health Sciences University, Edmonton, Alberta, Canada.
Theresa MottesAnn & Robert Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois.
Tara M NeumayrWashington University School of Medicine, St Louis, Missouri.
Zaccaria RicciUniversity of Florene, Florence, Italy.
David SelewskiMedical University of South Carolina, Charleston.
Danielle E SorannoRiley Children's Hospital, Indiana University, Bloomington.
Michelle StarrRiley Children's Hospital, Indiana University, Bloomington.
Natalja L StanskiCenter for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Scott M SutherlandLucille Packard Children's Hospital, Stanford University, Stanford, California.
Jordan SymonsSeattle Children's Hospital, Seattle, Washington.
Marcelo S TavaresSanta Casa de Belo Horizonte, Belo Horizonte, Minas Gerais, Brazil.
Molly Wong VegaDivision of Nephrology, Texas Children's Hospital, Baylor College of Medicine, Houston.
Michael ZappitelliThe Hospital for Sick Children, Toronto, Ontario, Canada.
Claudio RoncoUniversiti di Padova, San Bartolo Hospital, Vicenza, Italy.
Ravindra L MehtaUniversity of California, San Diego Health Sciences, San Diego.
John KellumUniversity of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Marlies OstermannGuys and St Thomas University, London, United Kingdom.
Rajit K BasuAnn & Robert Lurie Children's Hospital of Chicago, Northwestern University, Chicago, Illinois.
Pediatric ADQI Collaborative
Cincinnati Children's Hospital Medical Center · USAlberta Health · CALurie Children's Hospital · USChildren's of Alabama · USIndiana University Bloomington · USSeattle Children's Hospital · USThe Ohio State University · USUniversity of Iowa Stead Family Children’s Hospital · USUniversity of Pittsburgh Medical Center · USBaylor College of Medicine · USC. S. Mott Children's Hospital · USGolisano Children's Hospital · USGrupo Santa Casa de Belo Horizonte · BRHacettepe University · TRHospital for Sick Children · CAKing's College London · GBMayo Clinic · USMcMaster University · CAMedical University of South Carolina · USMercy Children's Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Renal Fitness in Young Adults with Congenital Heart DiseaseK23DK116973 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FUHRMAN, DANA YOUNG · 2019 to 2023
$1.2M
NCATS NIH HHS UL1 TR001425NCATS NIH HHS UL1 TR001863NIDDK NIH HHS K23 DK116973NIDDK NIH HHS L30 DK122411
6 · The paper itself

Abstract

Importance: Increasing evidence indicates that acute kidney injury (AKI) occurs frequently in children and young adults and is associated with poor short-term and long-term outcomes. Guidance is required to focus efforts related to expansion of pediatric AKI knowledge. Objective: To develop expert-driven pediatric specific recommendations on needed AKI research, education, practice, and advocacy. Evidence Review: At the 26th Acute Disease Quality Initiative meeting conducted in November 2021 by 47 multiprofessional international experts in general pediatrics, nephrology, and critical care, the panel focused on 6 areas: (1) epidemiology; (2) diagnostics; (3) fluid overload; (4) kidney support therapies; (5) biology, pharmacology, and nutrition; and (6) education and advocacy. An objective scientific review and distillation of literature through September 2021 was performed of (1) epidemiology, (2) risk assessment and diagnosis, (3) fluid assessment, (4) kidney support and extracorporeal therapies, (5) pathobiology, nutrition, and pharmacology, and (6) education and advocacy. Using an established modified Delphi process based on existing data, workgroups derived consensus statements with recommendations. Findings: The meeting developed 12 consensus statements and 29 research recommendations. Principal suggestions were to address gaps of knowledge by including data from varying socioeconomic groups, broadening definition of AKI phenotypes, adjudicating fluid balance by disease severity, integrating biopathology of child growth and development, and partnering with families and communities in AKI advocacy. Conclusions and Relevance: Existing evidence across observational study supports further efforts to increase knowledge related to AKI in childhood. Significant gaps of knowledge may be addressed by focused efforts.

Indexed as

Acute Kidney InjuryNephrologyChildCritical CareDelphi TechniqueHumans

Identifiers

PMID36178697
PMCPMC9756303
OpenAlexW4298086900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.