Evidence map›Paper›PMID 36178233›Full record

ArticleMagnetic resonance in medicine2022

Repeatability of B

Paul S Jacobs, Blake Benyard, Abigail Cember, Ravi Prakash Reddy Nanga, Quy Cao, M Dylan Tisdall, Neil Wilson, Sandhitsu Das, Kathryn A Davis, John Detre and 2 more

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. In Vivo Brain BNMR in biomedicine · 2025
    Article
  6. Review
  7. In vivoMagnetic resonance in medicine · 2024
    Article
  8. Mapping hippocampal glutamate in healthy aging withFrontiers in aging neuroscience · 2024
    Article
  9. Magnetic resonance in medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Paul S JacobsCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-3566-4010
Blake BenyardCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-2480-4164
Abigail CemberCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ravi Prakash Reddy NangaCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3644-5656
Quy CaoPenn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
M Dylan TisdallDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-0454-3112
Neil WilsonCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sandhitsu DasDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Kathryn A DavisDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
John DetreCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
David RoalfDepartment of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ravinder ReddyCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · USPenn Center for AIDS Research · US

Funding

High Spatial and Temporal Resolution MRI Mapping of Oxygen Consumption in HumansP41EB029460 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2021 to 2026
$7.6M
Ultra-high field GluCEST MRI and MRS in youth at risk for psychosisR01MH120174 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI ROALF, DAVID R · 2020 to 2024
$3.8M
Olfactory and facial markers of developmental risk for psychosis in 22q11 deletion syndromeR01MH119185 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI ROALF, DAVID R · 2019 to 2024
$3.5M
Optimized Intracranial EEG Targeting in Focal Epilepsy based upon Neuroimaging ConnectomicsR01NS116504 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DAVIS, KATHRYN ADAMIAK · 2021 to 2025
$3.3M
Imaging of glutamatergic system changes in Alzheimer's disease in vivoR01AG063869 · NIA · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2020 to 2024
$3.0M
Glutamate Chemical Exchange Saturation Transfer (GluCEST) Imaging in Cognitive AgingR56AG066656 · NIA · UNIVERSITY OF PENNSYLVANIA · PI ROALF, DAVID R · 2020 to 2020
$533k
NIA NIH HHS R01 AG063869NIA NIH HHS R56 AG066656NIBIB NIH HHS P41 EB029460NIMH NIH HHS R01 MH119185NIMH NIH HHS R01 MH120174NINDS NIH HHS R01 NS116504
6 · The paper itself

Abstract

purposeUltra-high field MR imaging lacks B THEORY AND

methodsGluCEST images were acquired on a 7T system on six healthy volunteers. Aqueous calcium titanate pads, with a permittivity of approximately 110, were placed on either side in the subject's head near the temporal lobes. A post-processing correction algorithm was implemented in combination with dielectric padding to compare contrast improvement. Tissue segmentation was performed to assess the effect of dielectric pads on gray and white matter separately.

resultsGluCEST images demonstrated contrast enhancement in the lateral temporal lobe regions with dielectric pad placement. Tissue segmentation analysis showed an increase in correction effectiveness within the gray matter tissue compared to white matter tissue. Statistical testing suggested a significant difference in gluCEST contrast when pads were used and showed a difference in the gray matter tissue segment.

conclusionThe use of dielectric pads improved the B

Indexed as

Glutamic AcidWhite MatterAlgorithmsGray MatterHumansMagnetic Resonance ImagingGlutamic AcidCESTdielectric padshigh field

Identifiers

PMID36178233
PMCPMC9529237
OpenAlexW4291889663

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.