Trial reportThoracic cancer2022
Comparison of ultrasound and mammography for early diagnosis of breast cancer among Chinese women with suspected breast lesions: A prospective trial.
Trial report in Thoracic cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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The trial behind it
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Who cites it
42 citing papers in PubMed, 54 citations in OpenAlex.
- Investigation of the effectiveness of cooling spray on mammography comfort.Scientific reports · 2025Trial
- Development and validation of a model and nomogram for breast cancer diagnosis based on quantitative analysis of serum disease-specific haptoglobin N-glycosylation.Journal of translational medicine · 2024Trial
- Comparison of ultrasound and mammography for early diagnosis of breast cancer among Chinese women with suspected breast lesions: A prospective trial.Thoracic cancer · 2022Trial
- Global research trends and thematic evolution of imaging-guided localization in breast cancer surgery: a bibliometric analysis.Gland surgery · 2026Article
- Deep learning-based Breast Imaging Reporting and Data System classification and establishment of diagnostic model in breast cancer diagnosis with automated breast ultrasound.Quantitative imaging in medicine and surgery · 2026Article
- A non-invasive end-to-end intelligent assistance system for breast ultrasound.Nature communications · 2026Article
- Utilizing post-imaging surveys to guide development of photoacoustic computed technology for breast imaging.American journal of surgery · 2026Article
- A cost-effective breast cancer screening strategy for Urban China: Findings from a Shenzhen-based modeling study.PloS one · 2026Article
- Development and External Validation of an Interpretable Machine Learning Model Using Routine Blood Biomarkers for Differentiating Malignant Breast Nodules.Journal of inflammation research · 2026Article
- Prognostic prediction model for triple-negative breast cancer using artificial intelligence and ultrasound radiomics.Frontiers in oncology · 2026Article
- Evaluation of the diagnostic accuracy of mammography and ultrasonography for breast cancer diagnosis using histopathology as the reference standard: a cross-sectional study.Annals of medicine and surgery (2012) · 2026Article
- Integrating Serum Lipid Biomarkers Into Machine Learning for the Differential Diagnosis of Breast Nodules.The breast journal · 2026Article
- Factors Associated With Preoperative Radiological Tumor Size Underestimation in Clinical T1-2 Breast Cancer Patients.The breast journal · 2026Article
- Diagnostic value of multimodal ultrasound imaging in triple-negative breast cancer.Frontiers in oncology · 2026Article
- Article
- Development and validation of an integrated model combining deep learning, radiomics, and clinical and breast ultrasound features for Breast Imaging Reporting and Data System 4A lesion malignancy classification.Quantitative imaging in medicine and surgery · 2025Article
- High-speed photoacoustic and ultrasonic computed tomography of the breast tumor for early diagnosis with enhanced accuracy.Science advances · 2025Article
- A novel tsRNA, tRF-33-6978WPRLXN4V0O inhibits breast cancer development via regulating PTEN/AKT pathway in BHLHA15-mediated manner.Journal of molecular medicine (Berlin, Germany) · 2025Article
- Diagnostic performance of ultrasound S-Detect technology in evaluating BI-RADS-4 breast nodules ≤ 20 mm and > 20 mm.BMC cancer · 2025Article
- Ultrasound-based radiomic nomogram for predicting the invasive status of breast cancer: a multicenter study.European journal of medical research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUltrasound is more widely used than mammography for early diagnosis of breast cancer in China as most Chinese women have small and dense mammary glands. This study compared the diagnostic performance of ultrasound and mammography for breast cancer among Chinese women with suspected breast lesions.
methodsFrom November 2019 to November 2021, we compared the results of ultrasound and mammography for breast lesion diagnosis in 2737 consecutive participants with suspected breast lesions; all patients underwent biopsies. We measured the sensitivity, specificity, and diagnostic accuracy separately.
resultsAmong the 2737 participants, 2844 breast lesions were detected, including 1935 (68.0%) breast cancers and 909 (32.0%) benign lesions. Of the breast cancers, ultrasound detected 1851 (95.7%), whereas mammography detected 1527 (78.9%). The sensitivity of ultrasound for breast cancer diagnosis was significantly higher than that of mammography (95.7% vs. 78.9%, p < 0.001), whereas the specificity was significantly lower than that of mammography (42.9% vs. 62.3%, p < 0.001). The receiver operating characteristic curves revealed that ultrasound was more accurate in detecting breast cancer than mammography (76.8% vs. 71.3%, p < 0.001). Age, body mass index, and breast density did not influence ultrasound sensitivity and accuracy.
conclusionsUltrasound is more sensitive and accurate than mammography and detects more breast cancers with a lower specificity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.