Evidence map›Paper›PMID 36177801›Full record

ArticleMolecular carcinogenesis2022

Energy balance-related factors in childhood and adolescence and risk of colorectal cancer based on KRAS, PIK3CA, and BRAF mutations and MMR status.

Josien C A Jenniskens, Kelly Offermans, Colinda C J M Simons, Iryna Samarska, Gregorio E Fazzi, Jaleesa R M van der Meer, Kim M Smits, Leo J Schouten, Matty P Weijenberg, Heike I Grabsch and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular carcinogenesis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Josien C A JenniskensDepartment of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0003-2727-2981
Kelly OffermansDepartment of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0001-6842-4887
Colinda C J M SimonsDepartment of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0002-0085-5186
Iryna SamarskaDepartment of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0003-4092-0672
Gregorio E FazziDepartment of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0001-7068-8435
Jaleesa R M van der MeerDepartment of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.
Kim M SmitsDepartment of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0002-4629-4396
Leo J SchoutenDepartment of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0003-3361-7560
Matty P WeijenbergDepartment of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0003-1695-4768
Heike I GrabschDepartment of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0001-9520-6228
Piet A van den BrandtDepartment of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0001-8781-8099
Maastricht University · NLUniversity of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

KRAS mutations (KRAS

Indexed as

Colonic NeoplasmsColorectal NeoplasmsDNA Mismatch RepairRectal NeoplasmsAdolescentAdultChildClass I Phosphatidylinositol 3-KinasesCohort StudiesFemaleHumansMaleMutationProto-Oncogene Proteins B-rafProto-Oncogene Proteins p21(ras)Young AdultBRAF protein, humanClass I Phosphatidylinositol 3-KinasesKRAS protein, humanPIK3CA protein, humanProto-Oncogene Proteins B-rafProto-Oncogene Proteins p21(ras)colorectal cancerearly-life energy balancemismatch repair/microsatellite instabilitymutationsprospective cohort study

Identifiers

PMID36177801
PMCPMC9828509
OpenAlexW4298086847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.