SynthesisClinical cardiology2022
Prognostic value of global longitudinal strain in hypertrophic cardiomyopathy: A systematic review and meta-analysis.
Synthesis in Clinical cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Subclinical Myocardial Dysfunction Assessment Using Speckle Tracking Echocardiography in Patients With Psoriasis: A Pilot Meta-Analysis.Clinical cardiology · 2024Pooled it
- Prognostic value of global longitudinal strain in hypertrophic cardiomyopathy: A systematic review and meta-analysis.Clinical cardiology · 2022Pooled it
- Association of Global Longitudinal Strain With Left Ventricular Remodeling and Left Ventricular Hypertrophy in Patients With Acute Myocardial Infarction After PCI: A Small Single-Center Prospective Observational Study.Health science reports · 2026Article
- Echocardiographic Global Longitudinal Strain and Myocardial Fibrosis in Patients with Left Ventricular Hypertrophy and Hypertrophic Cardiomyopathy.Biomedicines · 2026Article
- Unmasking the Apex: Multimodality Imaging for the Evaluation of Left Ventricular Apical Obliteration.Diagnostics (Basel, Switzerland) · 2026Review
- Exercise Stress Echocardiography Predicts Adverse Cardiovascular Events in Hypertrophic Cardiomyopathy: A 5-Year Prospective Study.Reviews in cardiovascular medicine · 2025Article
- Complementary classification of hypertrophic cardiomyopathy using unsupervised cluster analysis on left ventricular function.Scientific reports · 2025Article
- Echocardiographic Updates in the Assessment of Cardiomyopathy.Current cardiology reports · 2025Review
- Article
- Ultrasound speckle tracking imaging measurement of endocardial longitudinal strain for evaluation of prognostic value of "new quadruple" therapy in patients with chronic heart failure.Frontiers in endocrinology · 2025Article
- Apical Sparing of Longitudinal Strain as a Specific Pattern of Myocardial Fibrosis in Patients with Severe Left Ventricular Hypertrophy: A Comparison between Deformation Imaging and Histological Findings.Journal of clinical medicine · 2024Article
- Left ventricular strain-volume loops in bicuspid aortic valve disease: new insights in cardiomechanics.European heart journal. Imaging methods and practice · 2024Article
- Mexican guidelines 2024 for the diagnosis and treatment of hypertrophic cardiomyopathy.Archivos de cardiologia de Mexico · 2024Article
- The Role of Multimodality Imaging in Pediatric Cardiomyopathies.Journal of clinical medicine · 2023Review
- Does papillary muscle free strain has predictive value in risk stratification of patients with hypertrophic cardiomyopathy?PloS one · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs previously reported, impairment of left ventricular global longitudinal strain (LVGLS) is associated with myocardial fibrosis, arrhythmias, and heart failure in hypertrophic cardiomyopathy (HCM) patients. HYPOTHESIS: This study aimed to estimate the association between LVGLS measured by echocardiography and major adverse cardiovascular events (MACE) in patients with HCM.
methodsPubmed, Embase, Scopus, and Cochrane Library databases were systematically searched for evaluating the difference of LVGLS between MACE and non-MACE and the relevance of LVGLS and MACE in HCM patients, mean difference (MD), and pooled hazard ratios (HR) with 95% confidence interval (CI) were calculated. Publication bias was detected by funnel plots and Egger's test, and trim-and-fill analysis was employed when publication bias existed.
resultsA total of 13 studies reporting 2441 HCM patients were included in this meta-analysis. Absolute value of LVGLS was lower in the group of HCM with MACE (MD = 2.74, 95% CI: 2.50-2.99, p < .001; I
conclusionThe meta-analysis suggested that impaired LVGLS was associated with poor prognosis in HCM patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.