Evidence map›Paper›PMID 36177530›Full record

ReviewAngewandte Chemie (International ed. in English)2023

Photochemical Mechanisms of Fluorophores Employed in Single-Molecule Localization Microscopy.

Kai Kikuchi, Liam D Adair, Jiarun Lin, Elizabeth J New, Amandeep Kaur

Abstract readReview
In one paragraph

Review in Angewandte Chemie (International ed. in English), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Phenoxazines with a PhototransferableJournal of the American Chemical Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. On-Target Photoassembly of Pyronin Dyes for Super-Resolution Microscopy.Angewandte Chemie (International ed. in English) · 2025
    Article
  9. Review
  10. Review
  11. Photoactivation of BODIPY Fluorescence with Green Light.The Journal of organic chemistry · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kai KikuchiMedicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Melbourne, VIC 305, Australia.ORCID 0000-0002-4155-4101
Liam D AdairThe University of Sydney Nano Institute, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-9527-4869
Jiarun LinThe University of Sydney Nano Institute, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0003-2763-5463
Elizabeth J NewThe University of Sydney Nano Institute, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-2310-254X
Amandeep KaurMedicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Melbourne, VIC 305, Australia.ORCID 0000-0002-0898-875X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decoding cellular processes requires visualization of the spatial distribution and dynamic interactions of biomolecules. It is therefore not surprising that innovations in imaging technologies have facilitated advances in biomedical research. The advent of super-resolution imaging technologies has empowered biomedical researchers with the ability to answer long-standing questions about cellular processes at an entirely new level. Fluorescent probes greatly enhance the specificity and resolution of super-resolution imaging experiments. Here, we introduce key super-resolution imaging technologies, with a brief discussion on single-molecule localization microscopy (SMLM). We evaluate the chemistry and photochemical mechanisms of fluorescent probes employed in SMLM. This Review provides guidance on the identification and adoption of fluorescent probes in single molecule localization microscopy to inspire the design of next-generation fluorescent probes amenable to single-molecule imaging.

Indexed as

Fluorescent DyesSingle Molecule ImagingMicroscopy, FluorescenceFluorescent DyesFluorescencePhotochemistryPhotoswitchingSensorsSuper-Resolution

Identifiers

PMID36177530
PMCPMC10100239

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.