ArticleFrontiers in microbiology2022
Ruminal background of predisposed milk urea (MU) concentration in Holsteins.
Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- The role of milk urea nitrogen in nutritional assessment and its relationship with phenotype of dairy cows: A review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Review
- In anaerobic reactors the microbial community structure depends on feed type, with no "keystone" species tied to COD removal.Frontiers in microbiology · 2025Article
- Multi-tissue gene expression profiling of cows with a genetic predisposition for low and high milk urea levels.Animal biotechnology · 2024Article
- Mammary gland, kidney and rumen urea and uric acid transporters of dairy cows differing in milk urea concentration.Scientific reports · 2023Article
- Hepatic urea, creatinine and uric acid metabolism in dairy cows with divergent milk urea concentrations.Scientific reports · 2022Article
- The Benefits of Adding Sulfur and Urea to a Concentrate Mixture on the Utilization of Feed, Rumen Fermentation, and Milk Production in Dairy Cows Supplemental Fresh Cassava Root.Veterinary medicine international · 2022Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Efforts to reduce nitrogen (N) emissions are currently based on the optimization of dietary- N supply at average herd N requirements. The implementation of the considerable individual differences and predispositions in N- use efficiency and N- excretion in breeding programs is hampered by the difficulty of data collection. Cow individual milk urea (MU) concentration has been proposed as an easy-to-measure surrogate trait, but recent studies questioned its predictive power. Therefore, a deeper understanding of the biological mechanisms underlying predisposed higher (HMUg) or lower (LMUg) MU concentration in dairy cows is needed. Considering the complex N- metabolism in ruminants, the distinction between HMUg and LMUg could be based on differences in (i) the rumen microbial community, (ii) the host-specific transcription processes in the rumen villi, and (iii) the host-microbe interaction in the rumen. Therefore, rumen fluid and rumen epithelial samples from 10 HMUg and 10 LMUg cows were analyzed by 16S sequencing and HiSeq sequencing. In addition, the effect of dietary-N reduction on ruminal shifts was investigated in a second step. In total, 10 differentially abundant genera (DAG) were identified between HMUg and LMUg cows, elucidating greater abundances of ureolytic
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