ArticleFrontiers in bioengineering and biotechnology2022
A sustained release of alendronate from an injectable tetra-PEG hydrogel for efficient bone repair.
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 15 citations in OpenAlex.
- Fabrication and Characterization of Tetra-PEG-Derived Hydrogels of Controlled Softness.Macromolecules · 2025Article
- Injectable and high-strength PLGA/CPC loaded ALN/MgO bone cement for bone regeneration by facilitating osteogenesis and inhibiting osteoclastogenesis in osteoporotic bone defects.Materials today. Bio · 2024Article
- Rational construction of PCL-PEG/CS/AST nanofiber for bone repair and regeneration.Frontiers in bioengineering and biotechnology · 2024Article
- Alendronate-functionalized double network hydrogel scaffolds for effective osteogenesis.Frontiers in chemistry · 2022Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Significant efforts on construction of smart drug delivery for developing minimally invasive gelling system to prolong local delivery of bisphosphonates are considered as promising perspectives for the bone-related diseases, which provide the hydrogels with unique bioactivities for bone repair in clinic. Herein, we have constructed an alendronate (ALN)-conjoined injectable tetra-PEG hydrogel with excellent biocompatibility, uniform network, and favorable mechanical properties in one-pot strategy. In views of the quick ammonolysis reaction between N-hydroxysuccinimide (NHS)-ester of tetra-PEG-SG and amine groups of tetra-PEG-NH
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Registered trials
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