Evidence map›Paper›PMID 36176905›Full record

ArticleActa pharmaceutica Sinica. B2022

Combining immune checkpoint blockade with ATP-based immunogenic cell death amplifier for cancer chemo-immunotherapy.

Jiulong Zhang, Xiaoyan Sun, Xiufeng Zhao, Chunrong Yang, Menghao Shi, Benzhuo Zhang, Haiyang Hu, Mingxi Qiao, Dawei Chen, Xiuli Zhao

Open access · diamondAbstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jiulong ZhangSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xiaoyan SunSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xiufeng ZhaoDepartment of Oncology, Affiliated Hongqi Hospital of Mudanjiang Medical College, Mudanjiang 157011, China.
Chunrong YangDepartment of Pharmacy, Shantou University Medical College, Shantou 515041, China.
Menghao ShiSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Benzhuo ZhangDepartment of Neurology, The Second Affiliated Hospital of Mudanjiang Medical College, Mudanjiang 157009, China.
Haiyang HuSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Mingxi QiaoSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Dawei ChenSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Xiuli ZhaoSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
Shenyang Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amplifying "eat me signal" during tumor immunogenic cell death (ICD) cascade is crucial for tumor immunotherapy. Inspired by the indispensable role of adenosine triphosphate (ATP, a necessary "eat me signal" for ICD), a versatile ICD amplifier was developed for chemotherapy-sensitized immunotherapy. Doxorubicin (DOX), ATP and ferrous ions (Fe

Indexed as

ATPCoordination polymer nanoparticlesFenton reactionImmune checkpoint blockadeImmunogenic cell death amplifierPhenylboric acidpH/ROS sensitive

Identifiers

PMID36176905
PMCPMC9513492
OpenAlexW4280634506

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.