Evidence map›Paper›PMID 36176602›Full record

ArticleBioengineering & translational medicine2022

Developing a new treatment for superficial fungal infection using antifungal Collagen-HSAF dressing.

Jing Zhong, Xiayi Yan, Xin Zuo, Xuan Zhao, Jiahui Yang, Qin Dou, Lulu Peng, Yuxiang Zhu, Yichen Xiao, Zeran Bian and 7 more

Open access · goldAbstract read
In one paragraph

Article in Bioengineering & translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Hijacking competitor-derived signals: RcsB/C drivesApplied and environmental microbiology · 2026
    Article
  2. Review
  3. Mechanism ofApplied and environmental microbiology · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Jing ZhongState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou China.
Xiayi YanCollege of Marine Life Sciences, and Institute of Evolution & Marine Biodiversity Ocean University of China Qingdao China.
Xin ZuoState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou China.
Xuan ZhaoState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou China.
Jiahui YangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou China.
Qin DouCollege of Marine Life Sciences, and Institute of Evolution & Marine Biodiversity Ocean University of China Qingdao China.
Lulu PengState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou China.
Yuxiang ZhuCollege of Marine Life Sciences, and Institute of Evolution & Marine Biodiversity Ocean University of China Qingdao China.
Yichen XiaoState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou China.
Zeran BianCollege of Marine Life Sciences, and Institute of Evolution & Marine Biodiversity Ocean University of China Qingdao China.
Dalian HeState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou China.
Qiushuang XuKey Laboratory of Chemical Biology, School of Pharmaceutical Sciences Shandong University Jinan China.
Stephen WrightDepartment of Chemistry University of Nebraska-Lincoln Lincoln Nebraska USA.
Yaoyao LiKey Laboratory of Chemical Biology, School of Pharmaceutical Sciences Shandong University Jinan China.
Liangcheng DuDepartment of Chemistry University of Nebraska-Lincoln Lincoln Nebraska USA.
Yan WangCollege of Marine Life Sciences, and Institute of Evolution & Marine Biodiversity Ocean University of China Qingdao China.
Jin YuanState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center Sun Yat-sen University Guangzhou China.ORCID https://orcid.org/0000-0001-5756-5414
Sun Yat-sen University · CNMarine Biomedical Research Institute of Qingdao · CNShandong University · CNUniversity of Nebraska–Lincoln · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal pathogens are common causes of superficial clinical infection. Their increasing drug resistance gradually makes existing antifungal drugs ineffective. Heat stable antifungal factor (HSAF) is a novel antifungal natural product with a unique structure. However, the application of HSAF has been hampered by very low yield in the current microbial producers and from extremely poor solubility in water and common solvents. In this study, we developed an effective mode of treatment applying HSAF to superficial fungal infections. The marine-derived

Indexed as

A. fumigatus keratitisantifungal dressingcutaneous candidiasisheat stable antifungal factor (HSAF)superficial fungal infections

Identifiers

PMID36176602
PMCPMC9472023
OpenAlexW4214922342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.