Evidence map›Paper›PMID 36176578›Full record

ArticleFrontiers in cellular and infection microbiology2022

Harmine, an inhibitor of the type III secretion system of

Yunjia Shi, Xindi Chen, Jingyan Shu, Yang Liu, Yong Zhang, Qianghua Lv, Jianfeng Wang, Xuming Deng, Hongtao Liu, Jiazhang Qiu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Targeting Type III Secretion System usingIndian journal of microbiology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Naringenin targets FimZ to regulate type I fimbriae and reduce the virulence ofFrontiers in cellular and infection microbiology · 2025
    Article
  9. A Supramolecular Antibiotic Targeting Drug-ResistantACS applied materials & interfaces · 2024
    Article
  10. Review
  11. Fisetin inhibitsMicrobiology spectrum · 2024
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yunjia ShiLaboratory for Zoonotic Diseases, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Xindi ChenLaboratory for Zoonotic Diseases, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Jingyan ShuLaboratory for Zoonotic Diseases, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Yang LiuLaboratory for Zoonotic Diseases, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Yong ZhangDepartment of Respiratory Medicine, Center for Pathogen Biology and Infectious Diseases, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, State Key Laboratory for Zoonotic Diseases, The First Hospital of Jilin University, Changchun, China.
Qianghua LvLaboratory for Zoonotic Diseases, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Jianfeng WangLaboratory for Zoonotic Diseases, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Xuming DengLaboratory for Zoonotic Diseases, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Hongtao LiuLaboratory for Zoonotic Diseases, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Jiazhang QiuLaboratory for Zoonotic Diseases, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New therapeutic strategies for clinical

Indexed as

Salmonella typhimuriumType III Secretion SystemsAnimalsAnti-Bacterial AgentsBacterial ProteinsGene Expression Regulation, BacterialHarmineHeLa CellsHumansMiceSerogroupVirulence FactorsAnti-Bacterial AgentsBacterial ProteinsHarmineType III Secretion SystemsVirulence FactorsHarmineHilASPI-1S. Typhimuriumtype III secretion system

Identifiers

PMID36176578
PMCPMC9513467
OpenAlexW4295414647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.