Evidence map›Paper›PMID 36176524›Full record

ArticleFrontiers in public health2022

Modeling the health impact of legislation to limit the salt content of bread in Portugal: A macro simulation study.

Francisco Goiana-da-Silva, David Cruz-E-Silva, Ana Rito, Carla Lopes, Magdalena Muc, Ara Darzi, Fernando Araújo, Marisa Miraldo, Alexandre Morais Nunes, Luke N Allen

Abstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francisco Goiana-da-SilvaCentre for Health Policy, Institute of Global Health Innovation, Imperial College London, London, United Kingdom.
David Cruz-E-SilvaCenter for Innovation, Technology and Policy Research, IN+, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
Ana RitoNational Institute of Health, Porto, Portugal.
Carla LopesDepartment of Public Health and Forensic Sciences, and Medical Education, University of Porto Medical School, Porto, Portugal.
Magdalena MucAppetite and Obesity Research Group, Department of Psychological Sciences, University of Liverpool, Liverpool, United Kingdom.
Ara DarziDepartment of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, United Kingdom.
Fernando AraújoCentro Hospitalar Universitário São João, Faculty of Medicine, Porto University, Porto, Portugal.
Marisa MiraldoDepartment of Management, Centre for Health Economics and Policy Innovation, Imperial College Business School, London, United Kingdom.
Alexandre Morais NunesCentro de Administração e Políticas Públicas, Instituto Superior de Ciências Sociais e Políticas, Universidade de Lisboa, Lisboa, Portugal.
Luke N AllenLondon School of Hygiene and Tropical Medicine, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Excessive salt consumption-associated with a range of adverse health outcomes-is very high in Portugal, and bread is the second largest source. Current Portuguese legislation sets a maximum limit of 1.4 g salt per 100 g bread, but imported and traditional breads are exempted. In 2017 the Ministry of Health proposed reducing the salt threshold to 1.0/100 g by 2022, however the legislation was vetoed by the European Commission on free-trade grounds. Aims: To estimate the health impact of subjecting imported and traditional breads to the current 1.4 g threshold, and to model the potential health impact of implementing the proposed 1.0 g threshold. Methods: We gathered bread sales, salt consumption, and epidemiological data from robust publicly available data sources. We used the open source WHO PRIME modeling tool to estimate the number of salt-related deaths that would have been averted in 2016 (the latest year for which all data were available) from; (1) Extending the 1.4 g threshold to all types of bread, and (2) Applying the 1.0 g threshold to all bread sold in Portugal. We used Monte Carlo simulations to generate confidence intervals. Results: Applying the current 1.4 g threshold to imported and traditional bread would have averted 107 deaths in 2016 (95% CI: 43-172). Lowering the current threshold from 1.4 to 1.0 g and applying it to all bread products would reduce daily salt consumption by 3.6 tons per day, saving an estimated 286 lives a year (95% CI: 123-454). Conclusions: Salt is an important risk factor in Portugal and bread is a major source. Lowering maximum permissible levels and removing exemptions would save lives. The European Commission should revisit its decision on the basis of this new evidence.

Indexed as

BreadSodium Chloride, DietaryPortugalSodium Chloride, DietaryNCD and risk factorsnutritionpolicypublic healthsalt

Identifiers

PMID36176524
PMCPMC9513608

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.