Evidence map›Paper›PMID 36175847›Full record

ArticleBMC infectious diseases2022

Hemorrhagic fever with renal syndrome caused by destruction of residential area of rodent in a construction site: epidemiological investigation.

Xiao Wei, Biao Meng, Hong Peng, Yan Li, Min Liu, Hairui Si, Rui Wu, Hailong Chen, Ying Bai, Yan Li and 3 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Xiao Wei *Centers for Disease Control and Prevention of PLA, Beijing, China.
Biao Meng *Centers for Disease Control and Prevention of PLA, Beijing, China.
Hong PengCenters for Disease Control and Prevention of PLA, Beijing, China.
Yan LiCenters for Disease Control and Prevention of PLA, Beijing, China.
Min LiuPLA 63750 Hospital, Xi'an, Shaanxi, China.
Hairui SiPLA 63750 Hospital, Xi'an, Shaanxi, China.
Rui WuXi'an Center for Disease Control and Prevention, Xi'an, Shaanxi, China.
Hailong ChenXi'an Center for Disease Control and Prevention, Xi'an, Shaanxi, China.
Ying BaiPLA 63750 Hospital, Xi'an, Shaanxi, China.
Yan LiPLA 63750 Hospital, Xi'an, Shaanxi, China.
Qunling FengPLA 63750 Hospital, Xi'an, Shaanxi, China. 397068818@qq.com.
Changjun WangCenters for Disease Control and Prevention of PLA, Beijing, China. science2008@hotmail.com.
Xiangna ZhaoCenters for Disease Control and Prevention of PLA, Beijing, China. xnazhao@163.com.
Beijing Center for Disease Prevention and Control · CNAnhui Medical University · CNXian Center for Disease Control and Prevention · CN

Funding

Beijing Municipal Natural Science Foundation Project No. 5202027National Science and Technology Major Project No. 2018ZX10712001-12-2
6 · The paper itself

Abstract

backgroundAn outbreak of hemorrhagic fever with renal syndrome (HFRS), caused by a Hantavirus, affected nine adult males in the southwest area of Xi'an in November 2020 was analyzed in this study.

methodsClinical and epidemiological data of HFRS patients in this outbreak were retrospectively analyzed. The whole genome of a hantavirus named 201120HV03xa (hv03xa for short) isolated from Apodemus agrarius captured in the construction site was sequenced and analyzed. In addition, nine HFRS patients were monitored for the IgG antibody against the HV N protein at 6 and 12 months, respectively.

resultsIn this study, inhalation of aerosolized excreta and contaminated food may be the main source of infection. Genome analysis and phylogenetic analysis showed that hv03xa is a reassortment strain of HTNV, having an S segment related to A16 of HTN 4, an M segment related to Q37 and Q10 of HTN 4, and an L segment related to prototype strain 76-118 of HTN 7. Potential recombination was detected in the S segment of hv03xa strain. The anti-HV-IgG level of all the patients persist for at least one year after infection.

conclusionsThis report documented an HFRS outbreak in Xi'an, China, which provided the basic data for epidemiological surveillance of endemic HTNV infection and facilitated to predict disease risk and implement prevention measures.

Indexed as

Hemorrhagic Fever with Renal SyndromeOrthohantavirusAnimalsChinaMalePhylogenyRetrospective StudiesRodentiaHantaan virusHantavirusHemorrhagic fever with renal syndrome

Identifiers

PMID36175847
PMCPMC9521858
OpenAlexW4297991070

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.