Evidence map›Paper›PMID 36175739›Full record

ArticleDrugs & aging2022

Exploring Transplant Medication-Taking Behaviours in Older Adult Kidney Transplant Recipients: A Qualitative Study of Semi-Structured Interviews.

Amelia R Cossart, Christine E Staatz, Nicole M Isbel, Scott B Campbell, W Neil Cottrell

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In one paragraph

Article in Drugs & aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amelia R CossartSchool of Pharmacy, University of Queensland, Woolloongabba, 20 Cornwall Street, QLD, 4102, Australia. amelia.cossart@uqconnect.edu.au.ORCID 0000-0003-4032-6657
Christine E StaatzSchool of Pharmacy, University of Queensland, Woolloongabba, 20 Cornwall Street, QLD, 4102, Australia.
Nicole M IsbelDepartment of Nephrology, University of Queensland at the Princess Alexandra Hospital, Brisbane, Australia.
Scott B CampbellDepartment of Nephrology, University of Queensland at the Princess Alexandra Hospital, Brisbane, Australia.
W Neil CottrellSchool of Pharmacy, University of Queensland, Woolloongabba, 20 Cornwall Street, QLD, 4102, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundToday, older adult patients routinely undergo kidney transplantation. To support graft survival, patients must take immunosuppressant medicines for the rest of their lives. The post-transplant medication regimen is complex, and barriers to medication taking are likely confounded by both functional and intrinsic changes associated with advancing age. To develop diverse and innovative approaches to support best health outcomes in this vulnerable age group, it is imperative that the degree to which patients' needs are currently being met, be identified.

aimThe aim of this study was to examine medication-taking behaviours of kidney transplant recipients transplanted at 60 years of age or older.

methodsThis qualitative study used semi-structured patient interviews to explore how kidney transplant recipients currently manage their immunosuppressant regimen and how they cope after transplantation with the complex routine. Data were themed using the principles of Grounded Theory methodology; with interviews conducted until data saturation was reached.

resultsQuantitative information was collected from 14 participants who ranged in age from 66 to 77 years (at time of interview), and were prescribed a median of 13 (min: 10, max: 26) medicines. The main themes that emerged from the interview were variability in health literacy toward medicines, the importance of support networks, the need to adjust health expectations, factors that were motivators for self-care, different approaches to medication management, and different approaches to medication taking. Overall, it was found that patients prioritised medication taking above all else, and gratitude to their donor was a powerful motivator to adhere. However, strategies to support medication taking were sometimes ineffective when patients' routine changed.

conclusionsFuture interventions should consider approaches to foster adaptable medication taking behaviours that stand up to changes in the day-to-day routine.

Indexed as

Kidney TransplantationAgedHumansImmunosuppressive AgentsMedication AdherenceQualitative ResearchSelf CareImmunosuppressive Agents

Identifiers

PMID36175739
PMCPMC9626420

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