Evidence map›Paper›PMID 36175715›Full record

ReviewMedical oncology (Northwood, London, England)2022

The past, present, and future of immunotherapy for bladder tumors.

Theresa Schneider, Lei Zhao, Ziwen Zhu, Gagik Gabrielyan, Huaping Xiao, Emerson D Fajardo, Qian Bai, Mark R Wakefield, Yujiang Fang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Neoantigen immunotherapy: a novel treatment for bladder cancer.Exploration of targeted anti-tumor therapy · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Theresa Schneider *Department of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, IA, 50312, USA.
Lei Zhao *The Department of Respiratory Medicine, The 2nd People's Hospital of Hefei and Hefei Hospital Affiliated to Anhui Medical University, Hefei, China.
Ziwen ZhuDepartment of Surgery, University of Missouri School of Medicine, Columbia, MO, 65212, USA.
Gagik GabrielyanDepartment of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, IA, 50312, USA.
Huaping XiaoDepartment of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, IA, 50312, USA.
Emerson D FajardoDepartment of Surgery, University of Missouri School of Medicine, Columbia, MO, 65212, USA.
Qian BaiDepartment of Surgery, University of Missouri School of Medicine, Columbia, MO, 65212, USA.
Mark R WakefieldDepartment of Surgery, University of Missouri School of Medicine, Columbia, MO, 65212, USA.
Yujiang FangDepartment of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, IA, 50312, USA. yujiang.fang@dmu.edu.ORCID http://orcid.org/0000-0002-9107-7374
University of Missouri · USDes Moines University · USAnhui Medical University · CNXiangnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer is a prominent cancer worldwide with a relatively low survival rate for patients with increased stage and metastasis. Current treatments are based on surgical removal, bacillus Calmette-Guerin (BCG) Immunotherapy, and platinum-based chemotherapy. However, treatment resistance due to genetic instability of bladder tumors, as well as intolerance to treatment adverse effects leads to the necessity to further treatment options. New advancements in immunotherapy are on the rise for treatment of various cancers and specifically has shown promise in the treatment of bladder cancer. This review summarizes these new advancements in treatment options involving cytokines and cytokine blockade. Such a study might be helpful for urologists to manage patients with bladder cancer more effectively.

Indexed as

Urinary Bladder NeoplasmsBCG VaccineCytokinesHumansImmunologic FactorsImmunotherapyBCG VaccineCytokinesImmunologic FactorsBladder tumorImmunotherapyInterleukin

Identifiers

PMID36175715
OpenAlexW4297963727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.