Evidence map›Paper›PMID 36175648›Full record

Trial reportWorld journal of surgery2022

Validation of a Manual Negative Pressure Wound Therapy Device (PragmaVAC) for Acute and Chronic Wounds: A Prospective, Randomized, Controlled Trial.

Mahmoud Hariri, Bakry Maaz, Measser Netfagi, Jude Alawa, Ahmad Sattouf, Hussam Alden Dubies, Jehad Alahmad, Muhammet Fuat Seyitisa, Amandine Godier-Furnemont, Abedalkarem Ghali and 6 more

Erratum issuedAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Mahmoud HaririPragmatic Innovation Inc., Mississauga-Toronto, ON, Canada. m.hariri@sboms.org.ORCID 0000-0002-8669-7026
Bakry MaazMohamed Waseem Maaz Hospital, Northern Aleppo, Syria.
Measser NetfagiRahma Darkoush Hospital, Darkoush, Syria.
Jude AlawaStanford University School of Medicine, Stanford, CA, USA.
Ahmad SattoufIdleb Central Hospital, Idleb, Syria.
Hussam Alden DubiesIdleb Surgical Hospital, Idleb, Syria.
Jehad AlahmadSyrian Board of Medical Specialties (SBOMS), Gaziantep, Turkey.
Muhammet Fuat SeyitisaPragmatic Innovation Inc., Mississauga-Toronto, ON, Canada.
Amandine Godier-FurnemontDepartment of Surgery, University of California San Francisco, San Francisco, CA, USA.
Abedalkarem GhaliMohamed Waseem Maaz Hospital, Northern Aleppo, Syria.
Ahmad GhandourRahma Darkoush Hospital, Darkoush, Syria.
Zohair AbdullahRahma Darkoush Hospital, Darkoush, Syria.
Munther AlsalehMohamed Waseem Maaz Hospital, Northern Aleppo, Syria.
Ibrahim AlmousaIdleb Surgical Hospital, Idleb, Syria.
Waiel HabibIdleb Central Hospital, Idleb, Syria.
Hisham AlshaerPragmatic Innovation Inc., Mississauga-Toronto, ON, Canada.ORCID 0000-0001-6736-2215
Damascus Hospital · SYInternational University for Science and Technology · SYUniversity of Aleppo · SYStanford University · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNegative pressure wound therapy (NPWT) is an alternative to the standard gauze dressings for wound treatment. Due to limited health resources, poor electrical supply, and high costs, NPWT in resource-constrained settings is inaccessible. In conflict-affected settings, civilian injuries typically involve traumatic wounds or chronic wound infections that affect the extremities.

methodsPragmaVAC

resultsFifty-nine patients qualified for analysis (19 Gauze; 40 PragmaVAC). The mean age of participants was 49.25 years, 55.9% were male, and 42.4% were diabetic. Forty three wounds (72.9%) were acute, 44 wounds (74.6%) were clean-contaminated, and 34 wounds (57.6%) were localized to the lower limb. The average duration of treatment was 15.3 days in PragmaVAC vs 36.5 days in control, p = 0.013. Similarly, PragmaVAC required fewer number of dressing changes 2.7 vs 23.2 times, p < 0.0001, at a lower frequency of dressings 0.22/day vs 0.73/day, in the control group, p < 0.0001.

conclusionsPragmaVAC is associated with accelerated healing and less frequent requirement of dressing changes. The introduction of a manually operated, low-cost device in resource-constrained settings presents an opportunity to improve wound care outcomes, decrease interventions, and optimize usage of material and human resources.

Indexed as

Negative-Pressure Wound TherapyBandagesFemaleHumansMaleMiddle AgedProspective StudiesSurgical Wound InfectionWound Healing

Identifiers

PMID36175648
OpenAlexW4297996396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.