Evidence map›Paper›PMID 36175201›Full record

SynthesisJournal of the American Dental Association (1939)2022

Deep caries removal strategies: Findings from The National Dental Practice-Based Research Network.

M Marianne Jurasic, Suzanne Gillespie, Pina Sorbara, Janet Clarkson, Craig Ramsay, Denis Nyongesa, Deborah McEdward, Gregg H Gilbert, William M Vollmer, National Dental PBRN Collaborative Group

Registry-linked trialOpen access · greenAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of the American Dental Association (1939), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06256601 (A Clinical Investigation of the Effectiveness of a Calcium Silicate Cement Used in the Treatment of Deep Lesions), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06256601 nacompletednot on this mapstarted 2023, after this paper: background citation

A Clinical Investigation of the Effectiveness of a Calcium Silicate Cement Used in the Treatment of Deep Lesions

TypeinterventionalSponsorHacettepe UniversityRan2023 to 2026Enrolled80ConditionsDeep Caries, Dentin CariesArmsTheracal (calcium silicate), Dycal (calcium hydroxide)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Universal Dental Adhesives Containing Zinc Oxide and Copper Nanoparticles Improve Interface on Caries-Affected Dentin After 2 Years: In Vitro Study.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Article
  3. Management of deep caries.British dental journal · 2026
    Review
  4. Article
  5. Selective caries removal and management of exposed pulp in fully developed and immature teeth with reversible pulpitis: a questionnaire-based study in Greece.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

M Marianne Jurasic
Suzanne Gillespie
Pina Sorbara
Janet Clarkson
Craig Ramsay
Denis Nyongesa
Deborah McEdward
Gregg H Gilbert
William M Vollmer
National Dental PBRN Collaborative Group

Funding

The National Dental PBRN - Administrative CoreU19DE028717 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GILBERT, GREGG H · 2019 to 2025
$23.5M
NDPBRN Opioid SurveyU01DE028727 · NIDCR · KAISER FOUNDATION RESEARCH INSTITUTE · PI CARMIT Kurn MCMULLEN · 2019 to 2026
$16.0M
NIDCR NIH HHS U01 DE028727NIDCR NIH HHS U19 DE028717
6 · The paper itself

Abstract

backgroundThe International Caries Consensus Collaboration (ICCC) has published recommendations on carious tissue removal to treat cavitated carious lesions in a manner that preserves hard tissue and retains teeth long term. This study quantifies The National Dental Practice-Based Research Network dentists' use of selective caries removal.

methodsThis cross-sectional questionnaire study assessed reported use of selective caries removal when treating deep caries in asymptomatic and symptomatic teeth in response to clinical case scenarios. Statistical methods included the proportion of respondents concordant with ICCC guidelines at various thresholds and logistic regression to model factors associated with concordance.

resultsA total of 500 dentists responded. The study sample was 57% male, mean (SD) age was 50.9 (12.6) years, and 60% worked in private practice settings. Higher levels of concordance for choosing selective caries removal 50% or greater of the time were found for asymptomatic (62.4%; 95% CI, 57.6 to 67.2) than for symptomatic caries (49.3%; 95% CI, 44.4 to 54.2). These differences were significantly associated with type of practice setting.

conclusionsThe National Dental Practice-Based Research Network dentists reported using selective caries removal strategies when managing deep carious lesions more often than in previous US and Japanese practice-based research network studies and from results of a systematic review and meta-analysis. Nonetheless, substantive discordance with the ICCC guidelines was seen by the authors of this study. PRACTICAL IMPLICATIONS: More dissemination and continuing education activities, as well as implementation studies, may further encourage use of selective caries removal to soft or firm dentin when indicated.

Indexed as

Dental CariesToothCross-Sectional StudiesDental CareDental Caries SusceptibilityFemaleHumansMaleMiddle AgedPractice Patterns, Dentists'adultsdeep cariesSelective caries removal

Identifiers

PMID36175201
PMCPMC10787323
OpenAlexW4297215652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.