Evidence map›Paper›PMID 36174992›Full record

ArticleAllergy, asthma & immunology research2022

Multicenter Surveillance of Cystic Fibrosis in Korean Children.

Hyung Young Kim, Soo-Jong Hong, Kangmo Ahn, Dong In Suh, Shin Hye Noh, Soo Yeon Kim, Jinho Yu, Jung Min Ko, Min Goo Lee, Kyung Won Kim

Open access · diamondAbstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Clinical and Imaging Features of Cystic Fibrosis in Korean Children.Journal of the Korean Society of Radiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Hyung Young KimDepartment of Pediatrics, Dongnam Institute of Radiological & Medical Sciences, Busan, Korea.ORCID https://orcid.org/0000-0001-8591-1783
Soo-Jong HongDepartment of Pediatrics, Childhood Asthma Atopy Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-1409-2113
Kangmo AhnDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7751-9829
Dong In SuhDepartment of Pediatrics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7817-8728
Shin Hye NohDepartment of Pharmacology, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3118-9240
Soo Yeon KimDepartment of Pediatrics, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4965-6193
Jinho YuDepartment of Pediatrics, Childhood Asthma Atopy Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1226-8077
Jung Min KoDepartment of Pediatrics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0407-7828
Min Goo LeeDepartment of Pharmacology, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7436-012X
Kyung Won KimDepartment of Pediatrics, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. kwkim@yuhs.ac.ORCID https://orcid.org/0000-0003-4529-6135
Yonsei University · KRSeoul National University Hospital · KRUlsan College · KRDongnam Institute of Radiological & Medical Sciences · KRSamsung Medical Center · KR

Funding

National Research Foundation of Korea NRF-2013R1A3A2042197
6 · The paper itself

Abstract

purposeCystic fibrosis (CF), caused by mutations in the cystic fibrosis transmembrane conductance regulator (

methodsWe included 18 pediatric patients with CF diagnosed using sweat chloride test or genetic analysis for 30 years. HEK293 cells were transfected with wild-type

resultsThe median age at diagnosis was 9.2 years. Eleven patients had growth retardation, and 6 had a respiratory failure at diagnosis. Genetic analysis was used for all patients, while sweat testing was for 8 patients. At diagnosis, the median

conclusionsCF is extremely rare in Korean children and is caused by different mutations from those commonly observed in Caucasians. Early diagnosis and treatment availability may improve outcomes. CFTR modulators may be effective for Asian patients with rare

Indexed as

childCystic fibrosiscystic fibrosis transmembrane conductance regulatorKoreamutation

Identifiers

PMID36174992
PMCPMC9523417
OpenAlexW4298086673

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.