Evidence map›Paper›PMID 36174962›Full record

ArticleRespiratory physiology & neurobiology2023

The influence of CO

M Nicholas Musselwhite, Tabitha Y Shen, Melanie J Rose, Kimberly E Iceman, Ivan Poliacek, Teresa Pitts, Donald C Bolser

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory physiology & neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M Nicholas MusselwhiteDepartment of Physiological Sciences, College of Veterinary Medicine, University of Florida, 1333 Center Dr, Gainesville, FL 32603, United States. Electronic address: nick.musselwhite@me.com.
Tabitha Y ShenDepartment of Physiological Sciences, College of Veterinary Medicine, University of Florida, 1333 Center Dr, Gainesville, FL 32603, United States. Electronic address: tabitha.shen@gmail.com.
Melanie J RoseDepartment of Physiological Sciences, College of Veterinary Medicine, University of Florida, 1333 Center Dr, Gainesville, FL 32603, United States. Electronic address: meljrose@ufl.edu.
Kimberly E IcemanDepartment of Neurological Surgery and Kentucky Spinal Cord Injury Research Center, College of Medicine, University of Louisville, 511 S Floyd St, MDR 616, Louisville, KY, 40202, United States. Electronic address: kimberly.iceman@louisville.com.
Ivan PoliacekComenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Institute of Medical Biophysics, Malá hora 4A, 036 01 Martin-Záturčie, Slovakia. Electronic address: ivan.poliacek@uniba.sk.
Teresa PittsDepartment of Neurological Surgery and Kentucky Spinal Cord Injury Research Center, College of Medicine, University of Louisville, 511 S Floyd St, MDR 616, Louisville, KY, 40202, United States. Electronic address: t.pitts@louisville.edu.
Donald C BolserDepartment of Physiological Sciences, College of Veterinary Medicine, University of Florida, 1333 Center Dr, Gainesville, FL 32603, United States. Electronic address: bolser@ufl.edu.

Funding

Functional mapping of peripheral and central circuits for airway protection and breathingOT2OD023854 · OD · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C · 2016 to 2020
$10.8M
Modeling the role of the NTS in the neurogenesis of airway defensive behaviorsR01HL131716 · NHLBI · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C, MORRIS, KENDALL FRANCIS · 2017 to 2020
$3.1M
Central and Peripheral Regulation of Laryngeal AdductionR01HL163008 · NHLBI · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C, PITTS, TERESA G · 2022 to 2025
$2.8M
Influence of Opioids on the Brainstem Respiratory NetworkR01HL155721 · NHLBI · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C, MORRIS, KENDALL FRANCIS · 2021 to 2024
$2.7M
Central Mechanisms of Airway ProtectionR01HL103415 · NHLBI · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C, DAVENPORT, PAUL W · 2010 to 2013
$2.2M
NHLBI NIH HHS R01 HL103415NHLBI NIH HHS R01 HL131716NHLBI NIH HHS R01 HL155721NHLBI NIH HHS R01 HL163008NIH HHS OT2 OD023854
6 · The paper itself

Abstract

Effective cough requires a significant increase in lung volume used to produce the shear forces on the airway to clear aspirated material. This increase in tidal volume during cough, along with an increase in tidal frequency during bouts of paroxysmal cough produces profound hyperventilation and thus reduces arterial CO

Indexed as

Carbon DioxideHyperventilationAnimalsApneaCoughHypocapniaMaleRespirationCarbon DioxideAirway protectionCoughHyperventilationHypocapniaRespiratory control

Identifiers

PMID36174962
PMCPMC13063243

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.